August 2,19bb.

Deer Phnoia :

  Ed has auggestadthat I might be able to get aredit torrards r;lg Ph.D.

hew, on the basis of 14~ medical zsahool work, and the work on Naaxr>spora that

I did tith you. It might work, but he thought that it was a ticklish business

and that the better or more complete references were supplied, the more likely

the attempt to rmoceed. Could you dc the very great favor of sending a thorough

opinion of npr qualification8 for a dodorats in nicrobiology or genetiaa to
Dean Hart&y Simpson, Tale University Graduate School, New Haven,Ct. ?

The 8ex In bacteria Stuff would then be w thesfs. I have to emphasize the

extra-carriaular (extra PM) nork that I did.

  More recomMnation8 are uoming in3 we have non the four recolabinatiti

d.assss for two paira of characters : B-R-, R-R+, B+R- and B+R+, al&ho&h in

this cross, B-R- and B+R+ nere part8 of the parental types. But :he same thing

now for T-R+ and T+R- where T- ia threonlneleas, B- biotinless snd R+ resistance

to Tl. Al80 one more biochenrfcal recombination x R-T- (3 tines) fro@ B-#-C-

X T-P-. 1% have previously gotten B-P- from the 88~~ cro8s. There is not random

recombination of all characters, and our f&lure thusfar to isolate 8ome of

the other types can be accapnted for, by linkage, or possible s$&ective faatora,

but there is a real deficiency. Statistiaal analyslrs 8o far suggegts tlffo linkage
groups: threoninelest being in one, B,M,P,$, C, &&%x8xdand T in the other along

ulth R, TM.8 ie jumping a Tuttle rapidly however,  Y9 threMlias-leucine-'rnet~o~~

h~88~ is actually a pab-less; our old pab wa8 evidently impure and s
inhibitory. Alao a pab-lese In B/r. (Jrginlne-methionineless X Hfstidine-pablerr
in B/r have giver; no prototrophs.1

Regards to all, hoping to see you In a few weeks,