Further Observations on the Use of Pneumococcus Extracts in Effecting Transformation of Type In Vitro
Description:
A follow-up to the article Alloway published in early 1932 in which he demonstrated that by dissolving certain living pneumococci cells in sodium deoxycholate one could bring about transformation in vitro, rather than in laboratory mice as had previously been demonstrated. Through the process described in this article, he yielded the first soluble preparation of what would later become known as DNA.
Number of Image Pages:
14 (1,164,660 Bytes)
Date:
1933-02-01 (February 1, 1933)
Creator:
Alloway, J. Lionel
Source:
Periodical: Alloway, J. Lionel. "Further Observations on the Use of Pneumococcus Extracts in Effecting Transformation of Type In Vitro." Journal of Experimental Medicine 57, 2 (1 February 1933): 265-278. Article. 14 Images.
Publisher:
Rockefeller University Press
Rights:
Reproduced with permission of the Rockefeller University Press.
Subject:
Medical Subject Headings (MeSH):
Transformation, Genetic
Research Design
Exhibit Category:
Shifting Focus: Early Work on Bacterial Transformation, 1928-1940
Relation:
The Transformation In Vitro of R Pneumococci into S Forms of Different Specific Types by the Use of Filtered Pneumococcus Extracts (January 1, 1932)
Beitrage zur Variabilitat der Pneumokokken (1928)
The Interconvertibility of 'R' and 'S' Forms of Pneumococcus (April 1, 1928)
The Transformation of Pneumococcal Types In Vitro (1930)