The Elaboration of Specific Soluble Substance by Pneumococcus During Growth
Description:
Dochez and Avery discovered that culture fluids of pneumococci which were filtered to remove bacteria contained a substance in solution that precipitated when added to certain antisera, and which proved to be type specific. They reasoned that this component, which they called the "specific soluble substance," or SSS, was released in the body from the masses of pneumococci in the lungs of pneumonia patients and then excreted from the kidney and therefore present in patients' urine. Thus, it was possible to diagnose the type of pneumonia with which a person was infected by means of a simple urine test.
Item is a photocopy.
Number of Image Pages:
18 (1,389,575 Bytes)
Date Supplied:
2-3 May 1917
Creator:
Dochez, A. R.
Avery, Oswald T.
Source:
Periodical: Dochez, A. R., and Oswald T. Avery. "The Elaboration of Specific Soluble Substance by Pneumococcus During Growth." Transactions of the Association of American Physicians 32, ([2-3 May 1917]): 281-298. Article. 18 Images.
Publisher:
Blackwell Scientific Publications
Rights:
This item is in the public domain. It may be used without permission.
Exhibit Categories:
From Physician to Researcher: Early Laboratory Career and World War I, 1904-1919
The "Sugar-Coated Microbe" and the Search for a Cure for Pneumonia, 1919-1929
Relation:
The Soluble Specific Substance of Pneumococcus (June 1923)
Immunologic Relationships of Cell Constituents of Pneumococcus (June 1923)
The Soluble Specific Substance of Pneumococcus: Second Paper (August 1924)