August 1, 1961 Dr. L o Joseph Butterfield Department of Pediatrics University of Colorado Hedical Center Denver, Colorado My dear Doctor 3utterflsldt I: chortled aloud when I saw the epigram, It is very clever and certainly ori@nal, at Eoston Lying-In one day by a secretary, who said '3 didn't know Apgtir was a person, I thought it was just a thing," You might like to hear a greeting I received In reply to your ipestion about premies and the ticoring systen, I hare extrwted a feu figures f~m a paper which I hope to get finished t5fs month, whom 699 are under 200 grams. predictive value Df survival for tiny babies under 1000 grams, but in the other tieight groups, them are highly sic.rLficant differences. In it om discussed 30,000 babiers, of You are right that there is no If the three clinical states are compared (Poor-0,1,2,3; rair-4,5,6~ Gocd-7,8,9,10) u~ing neonatal death as the criteria for comparison, %he results &re as followsr P. - d.F. - Weight No. of Infants X2 - 5ol-moo gm8. 97 5.15 2 ,067 p > 005 l~l4.500 " 192 32 08 2 p <.ool l501-2OOo 409 37 .7 2 P < 2001-2500 1724 U8.4 2 P <.Wl Xf, in the smallest group, group of five and under (all the ood babies) are ontitted, since chi square is not reliable 5.n group hat sirre, the results do become significant. X2 = 7.8971, d.f. - 1, p( .01. Naturally, I belleve the results in a group of 698 inf'ants are nore reliable than in I& inf'anta in Boston, Dr. L. Jooeph Buttsrfiold August 1, 1961 Page 2 Stan ~~a6 at Prerrbyterhn Hoepitalhaa qate a bit of evidonce for a positive corrshtion of emore and rerpiratory di~trostc). pkudiaa Dssnoni at Baylor has much information abou% fib courie of infants of varying LICIOZW. IIope to see you the next time I am in Denver.