Letter from Michael Heidelberger to Kai O. Pedersen
Description:
Twice, in 1934 and 1936, Heidelberger received a John Simon Guggenheim Memorial Fellowship for a stay of six weeks at the University of Uppsala in Sweden, where he used the first ultracentrifuge, constructed by Theodor Svedberg and Kai O. Pedersen, to determine the molecular weight of various proteins, including antibodies in horse antipneumococcal sera. During his first visit, Heidelberger brought purified thyroglobulin, a protein secreted by the thyroid gland. In experiments completed by Pedersen after Heidelberger's departure and discussed by Heidelberger in this letter, the two found to their surprise that thyroglobulin was of high molecular weight.
Number of Image Pages:
3 (232,966 Bytes)
Date:
1935-02-15 (February 15, 1935)
Creator:
Heidelberger, Michael
Recipient:
Pedersen, Kai O.
Rights:
This item is in the public domain. It may be used without permission.
Subject:
Medical Subject Headings (MeSH):
Molecular Weight
Thyroglobulin
Ultracentrifugation
Exhibit Category:
Antigens and Antibodies: Heidelberger and The Rise of Quantitative Immunochemistry, 1928-1954
