Letter from Kai O. Pedersen to Michael Heidelberger
Description:
Twice, in 1934 and 1936, Heidelberger received a John Simon Guggenheim Memorial Fellowship for a stay of six weeks at the University of Uppsala in Sweden, where he used the first ultracentrifuge, constructed by Theodor Svedberg and Kai O. Pedersen, to determine the molecular weight of various proteins, including, during his second visit, antibodies in horse antipneumococcal sera. In experiments completed by Pedersen after Heidelberger's departure and discussed by Pedersen in this letter, the two found that these antibodies were of high molecular weight, another indication that they were, in fact, proteins.
Number of Image Pages:
4 (300,276 Bytes)
Date:
1936-10-20 (October 20, 1936)
Creator:
Pedersen, Kai O.
Recipient:
Heidelberger, Michael
Rights:
Reproduced with permission of Lennart Pedersen.
Subject:
Medical Subject Headings (MeSH):
Antibodies
Molecular Weight
Ultracentrifugation
Exhibit Category:
Antigens and Antibodies: Heidelberger and The Rise of Quantitative Immunochemistry, 1928-1954