YALE UNIVERSITY NEW HAVEN - CONNECTICUT DEPARTMENT OP BIOCHEMISTRY STERLING HALL. OF MEDICINE 333 CEDAR SI'RHBT 21 October 1955 Dr, Leon A. Heppel National Institutes of Health United States Public Health Service Bethesda, Maryland Dear Dr. Heppel, At the present time I am a graduate student in the Biochemistry Department at Yale University and expect to complete the work for the Ph, D, degree by September 1956, Dr, Joseph Fruton, my thesis director, suggested that I write to you concerning the possibility of spending a year in your laboratory as a post-doctordl fellow, I plan to apply to the National Science Foundation and the United States Public Health Service for a post-doctoral fellowship for the year 1956-57 and believe that the year would contribute greatly to my training if I could spend it working under your direction, I must explain that my own presence in the Washington area depends on my husband's success in obtaining a desired position, We will not know definitely about that until kch or April of 1956, and I wanted you to be aware of this situation in considering w application , My thesis problem is to study the enzyme phosphoamidase in beef spleen and thus far the work has included the preparation of syh%Wtic substrates, enzyme purification and the study of the properties of the partially purified preparation. $uring the first week of December I will be in Warshington and 1 could come and talk with you if that is convenient. If you would like a rem of my qualifications and education I would be happy to scIldc/fh ya w- 6L - mdu/cr ydy&I