October 14, 1959 Dr. Marianne Grunberg-Manago Institut de Biologie Physico-Chiltiique 13, Rue Pierre Curie Paris Ve, France Dear Eiar ianne , Wt a fine review'. I enjoyed reading it and I think the organization and completeness are admirable, A few minor correc- tions are included on another sheet; most of them could be disre- garded if you choose, except €or those concerning English grammar. By the way, the English is quite excellent throughout. How I wish I could do a tenth as well in French! I've been back at work since the beginning of September and I am fortunate to have a very fine woman to care for Amy, marvelous little girl she is--a good spirit, fine sense of humor and enthusiasm for everything about her. i rre s i st ab 1 e. What a Dan and I find her quite At the lab I'm busy with many things. manuscript and this time hope to get it completed. and I are talking about publishing a note on the S-RNA-polynucleo- tide phosphorylase data now that we are thoroughly convinced that the residual RNA (dubbed S-RNA-p) has the same s.a. for picking up active amino acid as does the starting material, information on the base analysis and end groups so there is a fair amount of material. you the manuscript before sending it off. a 5'-phosphomonoester end on Giulio's preps--which, as far as I can tell, is something new. Even more intriguing is that it appears to be all guan&e--that is the only 3' .5' diphosphate I've foundxpGp although I've looked €or the others. This is still new so time and more experiments are needed. I'm back at our old Also, Giulio Also we have Since you'll be an author on this we'll send I think I have identified Best regards to Armand and your little girl and congratula- Yours , tions on a fine manuscript. Enclosure Haxine Singer