CURRICULUM VITAE

Name:      Donald S. Fredrickson


Home Address:    6615 Bradley Boulevard, Bethesda, Maryland 20817


Date and Place of Birth:   August 8, 1924, Canon City, Colorado

Family:         Henriette Priscilla Dorothea Eekhof Fredrickson
            Two children: Eric H. and Rurik C.

Education:   University of Colorado, 1942-43
          B.S., University of Michigan, 1946
          M.D., University of Michigan, 1949
           Certified: American Board of Internal Medicine, 1957

Chronology of Employment:

1949-1950      House Officer, Peter Bent Brigham Hospital, Boston

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950-1951


950-1952


952-1953


953-1955
955-1961

James Jackson Cabot Research Fellow in Medicine,
   Harvard Medical School, Boston
Assistant in Medicine, Peter Bent Brigham Hospital,
    Boston
Research Fellow in Medicine, Massachusetts General
   Hospital, Boston
Clinical Associate, National Heart Institute, National Institutes of Health, Bethesda
Member, Senior Research Staff, Laboratory of Cellular Physiology

and Metabolism, National Heart Institute

961-1966


962-1966


966-1968
966-1974

             Heart Institute,

Head, Section on Molecular Diseases, Laboratory of
  Metabolism, National Heart 1nstitute;Bethesda

         isease Branch, National Heart and
   Lung Institute, Bethesda

1969-1974

1974-1975

-P -<rector of Intramural Research, National Heart, and
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   Lung Institute, Bethesda    i
                                            -q

President, Institute of Medicine, National Academy  \ h)G--

1975-1981
1981-1983


1983-1984


1984-1987


1987-

   of Sciences, Washington, D.C.
Director, National Institutes of Health, Bethesda 2 I-dj-4 Tp L-d-

Scholar-in-Residence, National Academy of Sciences,
   Washington, D. C.
Vice President, Howard Hughes Medical Institute,
    Bethesda
President, Chief Executive Officer and Trustee,
   Howard Hughes Medical Institute, Bethesda
President, DSF Associates, Inc., Bethesda

D.S. Fredrickson, M.D. Curriculum Vitae
March, 1996

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1987-         Scholar, National Library of Medicine, Bethesda

Present Related Professional Activities:

Advisory Committee, General Motors Cancer Research Foundation
Board of Directors, BSI, Inc.

Board of Directors, Foundation for Advanced Education in the Sciences
Board of Directors, Foundation for Biomedical Research
Chairman, National Library of Medicine Long Range Planning Panel on International Programs
Friends of the National Library of Medicine, Executive Committee
Life Sciences Research Foundation, Founding Board
Metropolitan Life Foundation Medical Research Awards Committee

Editorial Appointments:

Previous

American Journal of Medicine, Editorial Board
American Physiology Society, Member and Chairman, Publications

Committee

Circulation Research, Editorial Board
Health Affairs, Member of the Advisory Board
Issues in Science and Technology, Member of the Advisory Board
Journal of Atherosclerosis, Editorial Board
Journal of Clinical Investigation; Editorial/Advisory Boards
Journal of Lipid Research, Advisory Board
Physiology in Medicine, Advisory Board

Research Interests:

Lipoproteins, lipid transport and metabolism; medical genetics; biotechnology, academic and
industrial; science and public policy; medical and scientific institutions and education, medical
informatics

Honorary Degrees:

D. Med. (Hon.) Karolinska Institutet, 1977
D. SC (Hon.) University of Michigan, 1977
D. SC (Hon.) Mount Sinai School of Medicine, 1978
D. SC (Hon.) University of North Carolina, 1979
D. SC (Hon.) Yeshiva University, 198 1
D. SC (Hon.) Georgetown University, 198 1
D. SC (Hon.) University of Medicine and Dentistry of New Jersey, 1982
D. SC (Hon.) Medical University of South Carolina, 1985
D. SC (Hon.) George Washington University, 1985
D. SC (Hon.) University of Rochester, 1986

D.S. Fredrickson, M.D. Curriculum Vitae
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Memberships:

Alpha Omega Alpha

American Academy of Arts and Sciences
American Association for the Advancement of Science, Fellow
American College of Physicians, Fellow
American Philosophical Society
British Cardiac Society (Corresponding Member)
College of Medicine of Valencia (Honorary)
Cosmos Club

Deutsche Gesellschaft fur Innere Medizine (Corresponding Member)
Harvey Society (Honorary)
Institute of Medicine, National Academy of Sciences
Medical Society of Sweden (Honorary)
National Academy of Sciences
Peripatetic Club
Phi Beta Kappa
Phi Kappa Phi
Royal Academy of the Kingdom of Morocco
Royal College of Physicians, London (Fellow)

Emeritus Memberships:

American College of Cardiology, Fellow
American Federation for Clinical Research
American Heart Association, Council for the Study of Arteriosclerosis
American Physiological Society
American Society for Clinical Investigation
American Society of Human Genetics
Association of American Physicians
International Society of Cardiology
Society of Pediatric Research

Previous Related Professional Activities:

Chairman, Advisory Committee, Minority Faculty Development Program,
     The Robert Wood Johnson Foundation
Chairman, Committee on Medicine, Federal Coordinating Council for Science,
    Engineering and Technology

Chairman, Council on Arteriosclerosis, and Member, Board of Directors and
     Central Committee, American Heart Association
Chairman, Extramural Advisory Committee, University of California Irvine Health
          Science Center

Chairman, Federal Committee on Research on Biological Effects of
    Ionizing Radiation

D.S. Fredrickson, M.D. Curriculum Vitae
March. 1996

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Previous Related Professional Activities, Continued:

Chairman, Interagency Committee on Recombinant DNA Research (1976- 198 1)
Chairman and Member, Medical Board, NIH Clinical Center
Chairman, NIH Centennial National Advisory Committee (1988)
Chairman, Scientific Advisory Committee, Research America!
Chairman, TN0 Gaubius Laboratory Evaluation Team, Leiden (1992
Guest Researcher, Molecular Disease Branch, NHLBI, (1987- 199 1)
Lecturer in Preventive Medicine, Georgetown University School of Medicine,
    Washington, D. C.

Member, 1990 DHHS Advisory Committee on the National Institutes of Health
Member, Advisory Committee, University of Texas Health Science Center,
      Houston

Member, Advisory Council on Research, New York State Heart Association
Member, Board of Directors, Avon Products Inc.
Member, Board of Directors, Corange, Ltd.
Member, Board of Directors, Genetic Therapy Inc.
Member, Board of Directors, Greater Minnesota Corporation
Member, Board of Directors, Medlantic Research Foundation
Member, Board of Directors, Whitehead Institute for Biomedical Research
Member, Board of Overseers and the Board of Managers of Memorial
   Sloan-Kettering Cancer Center

Member, Board of Scientific and Medical Advisors, Amylin Corporation
Member, Board of Scientific Advisors, Buck Center
Member, Board of Scientific Advisors, Roche Institute of Molecular Biology
Member, Commonwealth Book Club
Member, Council and Executive Committee, National Academy of Sciences
Member, Cardiovascular Research Program Evaluation Committee, Veterans
    Administration

Member, Cardiovascular Study Section, NIH
Member, Charles A. Dana Foundation Awards Panel
Member, Committee on Fats, Food and Nutrition Board
Member, Committee for the Study of Inborn Errors of Metabolism,
    National Research Council

Member, Council, and Secretary-Treasurer, American Society of Clinical
          Investigation

Member, Council, Institute of Medicine
Member, Evaluation Panel, Fourth Medical & Health Research Program,
      Commission of the European Communities, 1990
Member, Evaluation Panel, An Evaluation of Science in Hungary, International
      Council of Scientific Unions, Budapest, I992
Member, Executive Committee, Assembly of Life Sciences,
        National Research Council

Member, Executive Committee, Section on Atherosclerosis,
      International Society of Cardiology
Member, External Advisory Committee, Department of Medicine,
      School of Medicine, University of Alabama, Birmingham
Member, External Advisory Committee, University of Texas Health
       Science Center, Dallas

D.S. Fredrickson, M.D. Curriculum Vitae
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Previous Related Professional Activities, Continued:

Member, Governing Board of the National Research Council (1982-1985)

National Academy of Sciences

Member, Hazen Prize Commmittee

Member, International Science Council, Foundation Cardiologique

   Princess Lilliane, Brussels
Member, Lasker Award Committee

Member, National Academy of Sciences Committee on Government-University

Relationships in Support of Science

Member, National Advisory Council for Research, Howard University
Member, National Council on Health Care Technology
Member, Nutrition Research Advisory Committee, National Dairy Council
Member, PolyVentures Science Advisory Board
Member, Research Advisory Board, E.I. du Pont de Nemours & Co.
Member, Research Council, Center for Prepaid Health Care
Member, Scientific Advisory Committee, California Biotechnology, Inc.
Member, Scientific Advisory Committee, Hapten Technologies Corp.
Member, Scientific Advisory Committee, Laser Recording Systems, Inc.
Member, Scientific Advisory Board, Scrippps Research Institute
Member, Stouffer Prize Committee

Member, White House Science Council (1982- 1989)
Member, Board of Trustees, Howard Hughes Medical Institute ( 1984- 1987)
Professorial Lecturer in Medicine, George Washington University School of
   Medicine, Washington, D.C.

U.S. Coordinator, Problem Area 1, Prevention of Arteriosclerosis
      U.S.-U.S.S.R. Cardiovascular Exchange, 1973

Honors and Other Special Scientific Recognition:

Alpha Omega Alpha

American College of Physicians Award
American College of Cardiology Distinguished Service Award
American College of Cardiology Gold Medal Award
American Heart Association Award of Merit
American Society for Clinical Nutrition McCollum Award
Arthur M. Sackler Foundation Award for Service to Science
Commandeur Ouissam Alaouite
Department of Health and Human Services Distinguished Public Service Award
Fondazione Lorenzini Medal (Milan)
Gairdner Foundation Award
Intrascience Award

James F. Mitchell International Award for Heart and Vascular Research
Jimenez Diaz Award (Madrid)
La Madonnina Prize for Science (Milan)
Lifetime Achievement Award, Sandoz Research Institute
Miami Winter Symposium Distinguished Service Award
Modem Medicine Distinguished Achievement Award

D.S. Fredrickson, M.D. Curriculum Vitae
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National Academy of Sciences
National Cholesterol Award for Public Health Scientific Achievement

Honors and Other Special Scientific Recognition Continued:

   New York Academy of Science Sarah L. Poiley Memorial Award
   Phi Beta Kappa
   Phi Kappa Phi
   Phi Rho Sigma Irving Cutter Medal
   Purkinje Award (Prague)
   Society of Research Administrators Distinguished Contribution to Research
Administration Award

Honorary Lectureships:

American Swiss Foundation for Scientific Exchange University Lectures
   (Basel, Bern, Lausanne, Geneva, Zurich), 1964
John Kent Lewis Memorial Lecture (Stanford), 1967
Seventeenth Annual Connvocation Lecture (American College of
   Cardiology), 1968

Third Bernard H. Pastor Memorial Lecture (University of

Pennsylvania), 1968

Marcus R. Caro Memorial Lecture (American Academy of Dermatology), 1968
The Carl Herzog Guest Lecturer (American Dermatological Association, 1969
The Distinguished Lecture (Association of American Physicians), 1969
Plenary Lecture, Deutsch Gesellschaft fur Klinische Chemie (Bonn), 1970
St. Cyres Lecture (National Heart Hospital, London), 1970
Wall Memorial Lecture (Children's Hospital of the District of

Columbia), 197 1

Cardiac Society of Australia and New Zealand and National Heart Foundation

Lecturer, 197 1

Alpha Omega Alpha Lecture and Visiting Professorship (Johns Hopkins

Medical School), 1972

Ernest William Goodpasture Lecture (Vanderbilt), 1972
John C. Higgins Memorial Lecture (University of Oregon), 1972
Harvey Lecture, 1973
Samuel Ballet Memorial Lecture (Philadelphia), 1973
The Jiminez Diaz Lecture (Madrid), 1974

Columbia University Bicentennial Lecture, 1976
Alpha Omega Alpha Lecture (Mount Sinai School of Medicine), 1976
G. Lyman Duff Memorial Lecture (American Heart Association), 1976
Wilson Day Address (University of Rochester), 1977
Irving S. Cutter Lecture (Phi Rho Sigma), 1978
Convocation Lecture (Mount Sinai School of Medicine), 1978
Wendell Scott Lecture (Washington University, St. Louis), 1978
Convocation Lecture (University of North Carolina), 1979
Geronimo Forteza Lecture (Valencia), 1979
Eugene A. Stead, Jr. Lecture (Duke Universitiy), 1980
Fiftieth Anniversary Lecture (British Research Society, London), 1980

D.S. Fredrickson, M.D. Curriculum Vitae
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   Commencement Address, Georgetown University Medical School, 198 1
   Commencement Address, University of Texas Medical Center (Houston), 198 1
   Public Lecture, American Association for the Advancement of Science,
       Annual Meeting (Washington, D.C.), 1982
Honorary Lectureships (cont.)

Alpha Omega Alpha Lecture (Baylor University School of Medicine), 1982
William Potter Lecture, Thomas Jefferson University (Philadelphia), 1982
Lilly Lecture, Royal College of Physicians (London/Leicester), 1982
Thorn Lecture, Peter Bent Brigham Hospital (Boston), 1982
Commencement Address, Cornell University Medical School, 1982
Presidential Lecture, Rice University, 1983
Commencement Address, Mayo Medical School, 1983
First Likoff-AOA Lecture, Hahnemann Medical School, 1984
Lewis Connor Memorial Lecture, American Heart Association, 1984
Commencement Address, The George Washington University, 1985
Albert Einstein Lecture, New York Academy of Sciences, 1985
75th Anniversary Lecture, The Rockfeller University Hospital, 1985
Anniversary Lecture, Harvard Medical School, 1986
Alpha Omega Alpha Visiting Professor Lecture, University of North Carolina

(Chapel Hill), 1987

  Keynote Address, Dedication National Research Council Facilities, 1987
  Plenary Lecture, NIH Centennial, 1987
  Speaker, Royal Academy of Maroc, Rabat, 1988
  Lecture, Tokyo University, 1989
  Speaker, Royal Academy of Maroc, Paris, 1989
  Chairman, Twentieth Annual Meeting, Institute of Medicine, 1990
  Symposium Speaker, Association of American Medical Colleges, 1990
  The Reynolds Lecture, U. Alabama Birmingham, 1991
  Lecture, National Library of Medicine, Lister Hill Center, 199 1
.`% First Donald S. Fredrickson Lecture on Lipoprotein Research
     International Atherosclerosis Society, October, 199 1
  Speaker, Royal Academy of Maroc, Casablanca, 1993
  Speaker, Cornell - N.Y. Hospital Policy Conference December, 1993
  Speaker, Columbia I-J. Conference Science. the Endless Frontier June, 1995

Bibliography: 260 publications.

February, 1997

D.S. Fredrickson, M.D. Curriculum Vitae
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