DEPARTMENT OF HEALTH, EDUCATION, AND WELFARE
             PUBLIC HEALTH SERVICE
        NATIONAL INSTITUTES OF HEALTH
               BETHESDA. MARYLAND 20205

January 21, 1981

The President
The White House
Washington, D.C. 20500

Dear Mr. President,

As is customary for President'al appointees,

I, Donald S. Fredrickson, Director of the National

Institutes of Health, offer my resignation to be

exercised at your pleasure.

Sincerely,

Donald S. Fredrickson, M.D.
Acting Secretary
Department of Health and Human Services
Director,  National Institutes of Health