This fourth chart compares the differences between ATP and GTP in dissociating pre-bound glucagon from a liver membrane cell receptor. As one can see by the charted lines in the upper right hand corner of the page, a smaller concentration of GTP could dissociate what a much larger concentration of ATP could accomplish in the same period of time. From these experiments, Rodbell concluded that, of all the nucleotides, GTP was the most effective biological catalyst.
Item is handwritten.
Number of Image Pages:
1 (227,938 Bytes)
Date Supplied:
ca. January 1970
Creator:
[Rodbell, Martin]
Rights:
Courtesy of Fernando Ribeiro-Neto.
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Subject:
Medical Subject Headings (MeSH):
Adenosine Triphosphate
Guanosine Triphosphate
Exhibit Category:
Signal Transduction and the Discovery of G-Proteins, 1969-1980
Relation:
Influence of Additions on Glucagon Binding (December 27, 1969)