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The Martin Rodbell Papers

Title:
The Glucagon-Sensitive Adenyl Cyclase System in Plasma Membranes of Rat Liver: I. Properties pdf (1,195,715 Bytes) ocr (39,101 Bytes)
Description:
The first in a now-classic series of five articles in which Rodbell concluded that GTP was likely the active biological factor in separating glucagon, a hormone that can act to increase blood glucose levels, from the cell's receptor, which had important implications for the treatment of various disorders and diseases.
Number of Image Pages:
8 (1,195,715 Bytes)
Date:
1971-03-25 (March 25, 1971)
Creator:
Pohl, Stephen L.
Birnbaumer, Lutz
Rodbell, Martin
Source:
Periodical: Pohl, Stephen L., Lutz Birnbaumer, and Martin Rodbell. "The Glucagon-Sensitive Adenyl Cyclase System in Plasma Membranes of Rat Liver: I. Properties." Journal of Biological Chemistry 246, 6 (25 March 1971): 1849-1856. Article. 8 Images.
Publisher:
American Society for Biochemistry and Molecular Biology
Rights:
Reproduced with permission of The American Society for Biochemistry and Molecular Biology.
Subject:
Medical Subject Headings (MeSH):
Adenylate Cyclase
Cell Membrane
Glucagon
Metabolism
Pharmacology
Exhibit Category:
Signal Transduction and the Discovery of G-Proteins, 1969-1980
Relation:
Metadata Record The Glucagon-Sensitive Adenyl Cyclase System in Plasma Membranes of Rat Liver: II. Comparison Between Glucagon- and Fluoride-Stimulated Activities (March 25, 1971)
Metadata Record The Glucagon-Sensitive Adenyl Cyclase System in Plasma Membranes of Rat Liver: III. Binding of Glucagon: Method of Assay and Specificity (March 25, 1971)
Metadata Record The Glucagon-Sensitive Adenyl Cyclase System in Plasma Membranes of Rat Liver: IV. Effects of Guanyl Nucleotides on Binding of 125 I-Glucagon (March 25, 1971)
Metadata Record The Glucagon-Sensitive Adenyl Cyclase System in Plasma Membranes of Rat Liver: V. An Obligatory Role of Guanyl Nucleotides in Glucagon Action (March 25, 1971)
Box Number: 19
Folder Number: 10
Unique Identifier:
GGAAAW
Document Type:
Articles
Language:
English
Format:
application/pdf
image/tif
Series: Laboratory Work and Research Publications, 1965-1997
SubSeries: Reprints
Folder: "Glucagon1-6 binds to the glucagon receptor and activates hepatic adenylate cyclase" (1979) TO "The glucagon-sensitive adenyl cyclase system in plasma membranes of rat liver. IV. Effects of guanylnucleotides on binding of 125I-glucagon" (1971)
Metadata Last Modified Date:
2006-04-06
U.S. National Library of Medicine, 8600 Rockville Pike, Bethesda, MD 20894
National Institutes of Health, Department of Health & Human Services
USA.gov, Copyright, Privacy, Accessibility
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