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The Martin Rodbell Papers

Title:
GTP Stimulates and Inhibits Adenylate Cyclase in Fat Cell Membranes through Distinct Regulatory Processes pdf (400,901 Bytes) ocr (15,374 Bytes)
Description:
The first of two articles in which Rodbell indicated that in addition to transducing hormone signals across the membrane, the G-protein could also inhibit signaling at the discriminator point. He provided evidence that G-proteins at the cellular receptors were sophisticated enough to both inhibit and activate signal transduction.
Number of Image Pages:
3 (400,901 Bytes)
Date:
1977-11-25 (November 25, 1977)
Creator:
Yamamura, Hirohei
Lad, Pramod M.
Rodbell, Martin
Source:
Periodical: Yamamura, Hirohei, Pramod M. Lad, and Martin Rodbell. "GTP Stimulates and Inhibits Adenylate Cyclase in Fat Cell Membranes through Distinct Regulatory Processes." Journal of Biological Chemistry 252, 22 (25 November 1977): 7964-7966. Article. 3 Images.
Publisher:
American Society for Biochemistry and Molecular Biology
Rights:
Reproduced with permission of The American Society for Biochemistry and Molecular Biology.
Subject:
Medical Subject Headings (MeSH):
Adenylate Cyclase
Guanosine Triphosphate
Hormones
Metabolism
Exhibit Category:
Signal Transduction and the Discovery of G-Proteins, 1969-1980
Relation:
Metadata Record Letter from Joshua Lederberg to Michael Doudoroff (November 22, 1948) (in The Joshua Lederberg Papers)
Box Number: 19
Folder Number: 12
Unique Identifier:
GGAABB
Document Type:
Articles
Language:
English
Format:
application/pdf
image/tif
Series: Laboratory Work and Research Publications, 1965-1997
SubSeries: Reprints
Folder: "G-proteins have properties of multimeric proteins: An explanation for the role of GTPases in their dynamic behavior' (1993) TO 'GTP stimulates and inhibits adenylate cyclase in fat cell membranes through distinct regulatory processes" (1977)
Metadata Last Modified Date:
2006-04-06
U.S. National Library of Medicine, 8600 Rockville Pike, Bethesda, MD 20894
National Institutes of Health, Department of Health & Human Services
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