Rodbell, writing in response to a request for a reprint of one of his articles from the series he published with Stephen L. Pohl and Lutz Birnbaumer, outlined in this letter some of their thinking on the role of guanine nucleotides in hormone action at the time the article was printed and how it has evolved since.
Number of Image Pages:
1 (79,956 Bytes)
Date:
1979-11-30 (November 30, 1979)
Creator:
Rodbell, Martin
Recipient:
Hall, Peter F.
Rights:
This item is in the public domain. It may be used without permission.
Subject:
Medical Subject Headings (MeSH):
Adenylate Cyclase
GTP-Binding Proteins
Guanine Nucleotides
Hormones
Exhibit Category:
Signal Transduction and the Discovery of G-Proteins, 1969-1980
Relation:
The Glucagon-Sensitive Adenyl Cyclase System in Plasma Membranes of Rat Liver: I. Properties (March 25, 1971)
The Glucagon-Sensitive Adenyl Cyclase System in Plasma Membranes of Rat Liver: II. Comparison Between Glucagon- and Fluoride-Stimulated Activities (March 25, 1971)
The Glucagon-Sensitive Adenyl Cyclase System in Plasma Membranes of Rat Liver: III. Binding of Glucagon: Method of Assay and Specificity (March 25, 1971)
The Glucagon-Sensitive Adenyl Cyclase System in Plasma Membranes of Rat Liver: IV. Effects of Guanyl Nucleotides on Binding of 125 I-Glucagon (March 25, 1971)
The Glucagon-Sensitive Adenyl Cyclase System in Plasma Membranes of Rat Liver: V. An Obligatory Role of Guanyl Nucleotides in Glucagon Action (March 25, 1971)