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The Julius Axelrod Papers

Title:
Studies on Sympathomimetic Amines. II. The Biotransformation and Physiological Disposition of D-Amphetamine, D-P-Hydroxyamphetamine and D-Methamphetamine pdf (1,146,989 Bytes) ocr (32,431 Bytes)
Description:
In this second in a series of papers by Axelrod on the role played in the body by sympathetic amines, a broad class of chemicals that mimic the actions of the sympathetic nervous system and have an amine basic structure, Axelrod found that the fate and physiological disposition of compounds of amphetamine in several species of animals was metabolized by a number of biochemical processes, including hydroxylation, demethylation, deamination, and conjugation. Axelrod again determined that various species showed considerable variations in the ways in which their bodies transformed these drugs.
Number of Image Pages:
13 (1,146,989 Bytes)
Date:
1954-03 (March 1954)
Creator:
Axelrod, Julius
Source:
Periodical: Axelrod, Julius. "Studies on Sympathomimetic Amines. II. The Biotransformation and Physiological Disposition of D-Amphetamine, D-P-Hydroxyamphetamine and D-Methamphetamine." Journal of Pharmacology and Experimental Therapeutics 110, 3 (March 1954): 315-326. Article. 13 Images.
Publisher:
American Society for Pharmacology and Experimental Therapeutics
Rights:
Reproduced with permission of the American Society for Pharmacology and Experimental Therapeutics.
URL: http://www.aspet.org/
Subject:
Medical Subject Headings (MeSH):
Biotransformation
Sympathomimetics
Metabolism
Exhibit Category:
Work on the Sympathomimetic Amines, 1946-1958
Relation:
Metadata Record Studies on Sympathomimetic Amines. I. The Biotransformation and Physiological Disposition of l-Ephedrine and l-Norephedrine (September 1953)
Metadata Record The Enzymatic Deamination of Amphetamine (Benzedrine) (June 1955)
Box Number: 22
Folder Number: 5
Unique Identifier:
HHAAAH
Document Type:
Articles
Language:
English
Format:
application/pdf
image/tif
Series: Writings and Publications, 1910-2003
SubSeries: Articles by Axelrod
SubSubSeries: Loose Reprints
Folder: Articles 1-280, 1948-1969
Metadata Last Modified Date:
2006-07-19
U.S. National Library of Medicine, 8600 Rockville Pike, Bethesda, MD 20894
National Institutes of Health, Department of Health & Human Services
USA.gov, Copyright, Privacy, Accessibility
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