The Distribution and Metabolism of Lysergic Acid Diethylamide
Description:
Late in the 1950s, Axelrod became interested in the distribution, excretion, metabolization and rate of "biotransformation" of lysergic acid diethylamide (LSD) by the body. In this first of several articles on the narcotic drug, he detailed the subcellular processes involved in the transformation of LSD, determined the order of concentrations of the drug in various tissues, determined that it was almost completely metabolized by the body, and found that their were considerable differences between various animal species in the rate of biotransformation of LSD.
Number of Image Pages:
10 (1,004,881 Bytes)
Date:
1957-03-14 (March 14, 1957)
Creator:
Axelrod, Julius
Brady, Roscoe O.
Witkop, Bernhard
Evarts, Edward V.
Source:
Periodical: Axelrod, Julius, Roscoe O. Brady, Bernhard Witkop, and Edward V. Evarts. "The Distribution and Metabolism of Lysergic Acid Diethylamide." Annals of the New York Academy of Sciences 66, (14 March 1957): 435-444. Article. 10 Images.
Publisher:
New York Academy of Sciences
Rights:
Reproduced with permission of the New York Academy of Sciences. Copies of Volume 66 are available through on-demand printing, and may be ordered directly from the Academy. Copies of individual articles may be ordered directly from the Academy or through Copyright Clearance Center.
Blood Levels of LSD 25 in Cat (February 10, 1955)