Celebrating Julie May 23,2005 NM Masur Auditorium Symposium Program 8:25-8:30 a.m. Welcome Thomas R. Insel, M.D., Director and Acting Scientific Director, National Institute of Mental Health (NIMH) Morning Session Chair Juan M. Saavedra, M.D., Chief, Section on Pharmacology, NIMH 8:30-8:45 a.m. Science with Julie, Pre- and Post-Nobel Irwin J. Kopiu, M.D., Scientist Emeritus, National Institute of Neurological Disorders and Stroke 8:45-9:30 a.m. Mechanisms of Neural Life and Death Solomon H. Snyder, M.D., Professor and Director, Department of Neurosciences; Johns Hopkins University 9:30-1O:OO a.m. Pharmacogenomics: Polymorphisms and Function Richard M. Weinshilboum, M.D., Professor of Pharmacology and Medicine, Mayo Clinic College of Medicine lO:OO-IO:30 a.m. 10:30- 1l:OO a.m. Coffee Break Endocannabinoids and Obesity - Is it Just the Munchies? George Kuuos, M.D., Ph.D., Scientific Director, National Institute on Alcohol Abuse and Alcoholism 11:00-l 1:25 a.m. Slow Transmission and Homeostasis at the Adrenomedullary Synapse Lee E. Eiden, Ph.D., Section on Molecular Neuroscience, NIMH 11:25- 11:40 a.m. A Brief Overview of the Pineal: Julie's Shmoo Martin Zatz, M.D., Ph.D., Chief Section on Biochemical Pharmacology, NIMH I 1:40- 12:00 noon The Magic Kingdom Michael J. Brownstein, M.D., Ph.D., Laboratory of Genetics, NIMH 12:00-12:25 p.m. Axelrod Video Tribute Introduced by Thomas R. Insel, M.D., Director, NIMH The Axelrod Legacy and the NIH Research Mission Elias Zerhouni, M.D., Director, National Institutes of Health 12:25-l :30 p.m. Lunch Break 1:30-1:35 p.m. Afternoon Greeting Thomas R. Insel, M.D., Director, NIMH Afternoon Session Chair Martin Zatz, M.D., Chief, Section on Biochemical Pharmacology, NIMH 1:35-2:05 p.m. 2:05-2:20 p.m. 2:20-2:45 p.m. 2:45-3:15 p.m. 3: 15-3:45 p.m. 3:45-4: 15 p.m. 4: 15-5:00 p.m. 5:00-5:05 p.m. Molecular Aspects of Catecholamine Metabolism, Uptake and Receptor Signaling in the Brain Marc G. Caron, Ph.D., Investigator and James B. Duke Professor, HHMI Department of Cell Biology, Duke University Medical Center A Chemist's Apprenticeship at the NIH John W. Daly, Ph.D., Scientist Emeritus, National Institute of Diabetes and Digestive and Kidney Diseases Protease Pathways for Peptides in Neurotransmission and Neurodegenerative Diseases Vivian Hook, Ph.D., Professor, Department of Pharmacology, University of California at San Diego Coffee Break NMDA Receptor Hypofunction and the Pathophysiology of Schizophrenia Joseph T. Coyle, M.D., Eben S. Draper Professor of Psychiatry and Neuroscience, Harvard Medical School The Anandamide Transporter - the Missing Link in Endocannabinoid Neurotransmission Christian Felder, Ph.D., Research Fellow, Neuroscience, Eli Lilly and Company Signal Transduction in the Brain Paul Greengard, Ph.D., Vincent Astor Professor, Laboratory of Cellular and Molecular Neuroscience, Rockefeller University Closing Remarks Thomas R. Insel, M.D., Director, NIMH