The Marshall W. Nirenberg Papers

Title:

Characteristics and Stabilization of DNAase-Sensitive Protein Synthesis in E. Coli Extracts

Description:

This innovative article is one of Nirenberg's most important early contributions to the coding problem. Published along with "The Dependence of Cell-Free Protein Synthesis in E. coli Upon Naturally Occurring or Synthetic Polyribonucleotides," this article provides experimental evidence that an extract prepared from bacterial cells can make protein even when intact living cells are not present. This revelation is a crucial step in the history of breaking the genetic code.

Number of Image Pages:

9 (842,397 Bytes)

Date:

1961-10 (October 1961)

Creator:

Matthaei, J. Heinrich

Nirenberg, Marshall W.

Source:

Periodical: Matthaei, J. Heinrich, and Marshall W. Nirenberg. "Characteristics and Stabilization of DNAase-Sensitive Protein Synthesis in E. Coli Extracts." Proceedings of the National Academy of Sciences 47, 10 (October 1961): 1580-1588. Article. 9 Images.

Publisher:

National Academy of Sciences

Rights:

Reproduced with permission of Marshall W. Nirenberg.

Subject:

Medical Subject Headings (MeSH):: Escherichia coli; Deoxyribonucleases

Exhibit Category:

Synthetic RNA and the Poly-U Experiments, 1959-1962

Relation:

The Dependence of Cell-Free Protein Synthesis in E. Coli Upon Naturally Occuring or Synthetic Polyribonucleotides (October 1961)

Unique Identifier:

JJBBDJ

Accession Number:

2001-009

Document Type:

Articles

Language:

English

Format:

application/pdf

image/tif

Physical Condition:

Good

Metadata Last Modified Date:

2006-04-07

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