RNA Codewords and Protein Synthesis, II. Nucleotide Sequence of a Valine RNA Codeword
Description:
After the poly-U experiments, the next major challenge was finding out what the remaining codewords were. In this article, the authors use a rapid method for measuring sRNA binding to ribosomes and try to resolve some problems with ambiguous and synonymous codewords. The experimental evidence suggests the binding of specific types of sRNA to ribosomes is directed by only certain corresponding trinucleotides, making sequencing efforts more feasible in the coding process.
Item is a photocopy.
Number of Image Pages:
8 (778,972 Bytes)
Date:
1964
Creator:
Leder, Philip
Nirenberg, Marshall W.
Source:
Periodical: Leder, Philip, and Marshall W. Nirenberg. "RNA Codewords and Protein Synthesis, II. Nucleotide Sequence of a Valine RNA Codeword." Proceedings of the National Academy of Sciences 52, (1964): 420-427. Article. 8 Images.
Publisher:
National Academy of Sciences
Rights:
Reproduced with permission of Marshall W. Nirenberg.
Subject:
Medical Subject Headings (MeSH):
RNA
RNA, Messenger
Ribosomes
Amino Acids
Exhibit Category:
Translating the Code of Life and the Nobel Prize, 1962-1968
