Genes for Neuronal Properties Expressed in Neuroblastoma x L Cell Hybrids
Description:
As part of Marshall Nirenberg's early work in neurobiology, this early article uses neuroblastoma systems to explore steps in the maturation process as well as aspects of neural function. Somatic cell hybrids are shown to possess the "neuronal property of electrically excitable membranes." The authors hope to apply these findings to promote neuronal differentiation in normal neuroblasts. The article provides evidence that "at least part of the genetic information for neuron differentiation can be functionally expressed in" hybrid cells.
Item is a photocopy.
Number of Image Pages:
6 (834,351 Bytes)
Date:
1971-01 (January 1971)
Creator:
Minna, John
Nelson, Phillip
Peacock, John
Glazer, Devera
Nirenberg, Marshall W.
Source:
Periodical: Minna, John, Phillip Nelson, John Peacock, Devera Glazer, and Marshall W. Nirenberg. "Genes for Neuronal Properties Expressed in Neuroblastoma x L Cell Hybrids." Proceedings of the National Academy of Sciences 68, 1 (January 1971): 234-239. Article. 6 Images.
Publisher:
National Academy Press
Rights:
Reproduced with permission of Marshall W. Nirenberg.
