STATE UNIVERSITY OF NEW YORK DOWNSTATE MEDICAL CENTER 450 CLARKSON AVENUE, BROOKLYN, NEW YORK 11203 AREA CODE 212 270.1000 COLLEGE OF MEDICINE Department of Surgery Division of Neurosurgery April 6, 1969 Dr. Edward F. MacYichol, Jr. Director National Institute of Neurological Diseases & Stroke National Institutes of Health Bethesda, Maryland Dear Dr. MacNichol, I read with intense Interest your address to the program directors's workshop for neurosurglcal training held In Denver Colorado, Jan. 22-24, 1969, I agree that there is need for neurosurgeons who are better versed In the basic -.research areas. My increasing frustration in clinical neurosurgery specifically, the treatment of malignant brain tumors, goads me to assume increasing interest in the more basic areas I.e. molecular biology where,hopefully, one may find the ~~~n~to~~-lncreasingly frustrating problem. It has reached the point that I am willing to spend 2 or more years as some kind of a fellow In order to delve into the problem in depth. I womder if I cou Id g&some advice from you in this regard specially the where, how and what in terms of fellowship application. I am a board-certified neurosurgeon holding a full time academic appointment at the above institution. I have had 1 l/2 yeard research experience In neuropathology with some electronmicroscopy and for the past X l/2 years,have spent almost full time working in the laboratory of micro-neurochemistry, I have In mind working with either Dr. Francis Crick or Dr. James Watson, the former in Cambridge, I would appreciate your &pinion regarding the matter. Thank you for your consideration. Sincerely y9ys, L&L.&+ ,.<-',,-.z-,, William Cuatico, M.D., FACS Assistant Profeseor COLLEGE OF MEDICINE o SCHOOL OF GRADUATE STUDIES. UNIVERSITY HOSPITAL. COLLEGE OF NURSING . COLLEGE OF HEALTH RELATED PROFESSIONS Watson has recently become interested in oncogenic viruses so this would be good. Sidney Brenner rather than Francis Crick is working on the nervous system in Cambridge, Bob Spiegelman will be moving to Columbia in July and is interested primarily in the cancer problem. Probably Watson and Spiegelman's interests are closest to Cuatico's.