UNIVERSITY OF CALIFORNIA COLLEGE OF AGRICULTURE AGRICULTURAL EXPERIMENT STATION DEPARTMENT OF BOTANY 405 HILGARD AVENUE LOS ANGELES 24, CALIFORNIA 3r. R. Franklin Birkbeck College University of London London, England Dear Miss Franklin, It was indeed a pleasure to meet you on your recent visit to this country. You expressed a desire to examine some strains of THV which differ appreciably from the common strain. I am, therefore, sending you a sample of our U2 strain which differs from the common strain in quite a number of properties, some of which are described in a paper which I am sending under separate cover, The sample consists of 10 cc containing 17 mg virus per cc, It is made up in 0.1 ionic strength cacodylic acid buffer which is 0.08 M NaC1. changes of water in order to get rid of the salts, should you so desire. You need only dialyze this solution through several We would appreciate learning of any progress that you might make with this material.. whether any of the differences that we have observed between strains is correlated with differences in the structure of the molecules. It would be interesting to find out