-`~~~~igh-ti~-g7Swi~e-FIu' ,To -KEditor: . The `news article. "Researchers Find -La.rge-&oses-of-Vitamin-C-May-Dam=- age-Gene Mater&l" (May 20) describes observations by a research. team in. a _. Aoxjrgen--+nucleic-acids-and--Rroteins- has been known for several years. It -leads .to inactivation of ' viruses and contributes to the ,control `of viral diseases-by-vitamin-C-A-ha& evident that animals: have some-mech; anism to,piatect their genetic *material ~-e~~~~~r-R-~~a~c~-~~~~~~-~~~~~~ against this-sort-of-damage. For ex- -.- .-__.._ ,vniversity_lof-British._Coiumbia on the / .._I._. imei-.Y tiutagenic act&- of ascorbic - acid, arnp~~,~~e-mou~e~hawj_a -.low~!ut+- ,metal ions and oxygen, and quotes ' tion rate, even though `it manufactures vitamin C in its own cells rit a rate- one or up2 ~tmesofgarms z3 suggesung 7mrqmdi~fnanilnrawenFni~s that .- peopie --. shot&l.- -"anatb-massiE doses of vitaniin C." I have advocated -grams. or the- vitamin-.perAay-ror-a. Ahe-u~~~f?Yi.tW%C in amounts of mgn. It .is ,likely ,t,hat human beings --E--._-.m .._.__ _ _. several -grams--per day- to- prevent or haves: the--same protective me&anlsn+ _. .-- _- .tr&t the common cold and other in- and thatthere is little-&nger;of harm- fectious diseases, including influenza, ful effects from ingesting the amounts -and `I think. that it may be of impor- of vitamin C, several grams per day, t&e in relation' to the expect*. epi- that most animals synthesize for them- -selves.- ___ _- L_. . . _- -demic,.of-swine-. fIrthat-yople-- not - I_- _ __ LLil?vs_P4V&1_N_c be; discouraged -from-:mpking pr,oper Linus l$rlinglInstitute of use of `this---valuable substance. The Science and MeUfcine ' -acti& of ascorbic acid, metal ions and Menlo Park, Calif;, May 21, i976