~cs  03/06/79 informatics inc    6911 Kenil-h *mm    cs IV

INDEX

ABRUPT10 PLACENTAE
(See a&o PERINATAL MORTALITY)
maternal smoking levels and, 3, 7
smokers vs. nonsmokers, 3, 8
ADOLESCENTS
smoking habit, 50, 52
ADVERTISING
effect on cigarette consumption, 52
    53
AGING

effect on mortality ratios in smokers,
  28

effect on mortality ratios in ex-
smokers, 36-37

AMERICAN CANCER SOCImY
  STUDY

methodology, 2526
ANTISMOKING CAMPAIGNS
(See also PREVENTION OF SMOK-
ING)
short and long term strategies, 43-50
BIRTH WEIGHT
effect of carbon monoxide in rabbits,
    12

effect of cewation of smoking during
PEgnanCY, 2

effect of maternal smoking, 14
fetal and maternal carboxyhemoglo-
   bin levels and, 9-10
matemal smoking and, 11, 13
BLOOD VESSELS
effect of carboxyhemoglobin on fetus
   and placenta, 9
effect of smoking, 13
BREAST FEEDING
(See aleo LACTATION)
effect of nicotine on infanta, 15
BRITISH DOCTORS STUDY
methodology, 26!Z7
CARBON MONOXIDE
effect on pregnancy, 9-13

effect on birth weight and neonatal
   mortality in rabbits, L2
low birth weight infants and, 12
CARBOXYHEMOGLOBIN
effect on fetal and placental blood
   vessels, 9

effect on oxygen transport in fetw
  11

CARBOXYHEMOGLOBIN LEVELS
birth weight and, 9-10
birth weight in rabbits and, I2
effect of maternal smoking on fe-
   tavmatemal ratio, 11
effect of smoking in pregnant vs.
  nonpregnant women, 9-10
CARDIOVASCULAR DISEASES
(See also ISCHEMIC HEART DISEASE;
MYOCARDIAL INFARCT;
THROMBOEMBOLISM)
mortality risk in oral contraoeptive
   users and smokers, 13-14
oral contraceptives and smoking and,
   13-15

CESSATION OF SMOKING
(See aho EX-SMOKERS; SMOKERS
vs. Ex-sMOKERs)
effect on biih weight in offspring,
    2

effect on ischemic heart d&ease mar-
tality risk, 36

effect on lung neoplasm mortality
risk, 37

effect on mortality ratea and ratios,
32-37,4142

health benefits, 43-50
CHILDREN
effect of maternal smoking during
  pregnancy on intellectual and
  physical development, &9
smoking habit., 50, 52

57


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INDEX

CIGARETTE CONSUMPTION
effect of t&acco industry advertis-
   ing,5%53

CIGARElTES, LESS HAZARDOUS
health benefits, 43-49
mortality ratios in low va medium
   vs. high tar/nicotine smokers, 30-
   31

mortality ratios in low tar/nicotine
   smokers vs. nonsmokers, 31
coNTRAcEPTIvEs, ORAL
eardiovascldar ciileaw and smoking
   and, l3-15

myocardial infarct and smoking and,
    1815
DDT

effect of maternal smoking on levels
   in breast milk, 15
EX-SMOKERS

(See ah CESSATION OF SMOKING;
SMOKERS vs. Ex-sM0KEss)
bii weight in offspring, 2
mortality ratios, 32-33
FETUS

(See aleo BIRTH WEIGHT; PERINA-
TAL MORTALITY)
effect of carboxyhemoglobin on blood
   vessele, 9

effect of maternal smoking on oxy-
   gen transport, 11-12
HEREDITY

role in disease etiology, 49
INHALATION

effect on mortality ratios in ciga-
   rette smokera, 29
effect on mortality ratios in cigar vs.
  pipe smokers, 33
INTELLECTUAL DEVELOPMENT
effect of maternal smoking levels
  during pregnancy on offspring,
   3-9

ISCHEMIC HEART DISEASE
(Ses also CARDIOVASCULAR DIS-
EASES)
mortality risk, effect of cessation of
   smoking, 36
LACTATION
(See also BREAST FEEDING)
effect of maternal smoking, 15
LUNG NEOPLASMS
mortality risk, effect of cessation of
   smoking, 37

MORTALITY

annual probability of dying in smok-
  em va nonsmokers
va ex-smokers, 34-37
cardiovascular diwases, risk in oral
contraceptive users and smoke=,
  13-14

cigarette va cigar vs. pipe smokers,
  38

effect of smoking, 21-45
my&al infarct, rati in orai con-
traceptive users and smokers, l3-
  14

summary of the 1964 Surgeon Gener-
  al's Report findinga, Z-23
summary of the 196'7 He&h Con&?-
   qutmeea of Smoking findings, 29
MORTALITY RATIOS
cigarette va cigar vs. pipe smokers,
   38, 41-45

effect of inhalation, 29$3
effect of smoking duration in cigar
smokers, 39

effect of smoking duration in ciga-
  rette smokers, 2829
effect of smoking duration in pipe
  smokers, 39-41

effect of smoking levels in cigar
smokers, 39-40

effect of smoking levels in cigarette
smoke-m, 27-29

effect of smoking levels in pipe
  smokers, 39-41

ex-smokere, 32-37
low tar/nicotine smokera va non-
smokers, 31-32

low vs. medium va high tar/nicotine
   smokem, 33, 41-43
MYOCARDIAL INFARCT
(See also CARDIOVASCULAR DIS-
  EASES)
mortality rate in oral contraceptive
   users and smokers, 13-14
oral contraceptivea and smoking and,
    13-15

NATIONAL CHILD DEVELOPMENT
  STUDY, 3-9

NATIONAL CLEARINGHOUSE FOR
  SMOKING AND HEALTH
effect of maternal smoking on preg-
   nancy, survey of public aware-
   ness, 16

role in prevention of smoking, 55


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INDEX

NICOTINE

rffect on breastcfed infants, 15
effect on mortality ratios, 30-31
NEONATAL MORTALITY
effect of carbon monoxide in rabbits,
   12

ONTARIO PERINATAL MORTALITY
STUDY, 3

OXYGEN TRANSPORT

effect of carboxyhemoglobin on
    fetus, 11
*  effect of maternal smoking on fetus
    and mother, 11-12
' pSRINATAL MORTALITY
(,$ee also ABRUPT10 PLACENTAE;
  BIRTH WEIGHT; PLACENTA
  PREVIA; PREMATURITY; STILL-
  BIRTHS)
effect of maternal smoking, 23, 7
  maternal smoking and, 13
  risk factors, 2-3
PHYSICAL DEVELOPMENT
effect of maternal smoking levels
   during pregnancy on offspring,
     a-9
PLACENTA

effect of carboxyhemoglobin on blood
vessels, 9

PLACENTA PREVIA
(See also PERINATAL MORTALITY)
maternal smoking levels and, 3-4, 7
smokers vs. nonsmokers, 3-4, 8
PREGNANCY

effect of carbon monoxide, 9-13
effect of maternal smoking, 1-13
effect of maternal smoking, public
   awareness, 1516
PREMATURITY
(se also FETUS; PERINATAL MOR-
TALITY)
maternal smoking levels and, 3-4
PREVENTION OF SMOKING
(See atso ANTISMOKING CAM-
PAIGNS)
barriers to successful control, %-%
health benefits, 43-56
international programs, future needs,
    55-56

SMOKE, CIGARETTE
(See also SMOKING)
synergistic action in disease etiology,
   49

SMOKERS, CIGAR
mortaiity ratios, 33-43
mortality ratios, effect of smoking
   duration 33-39

mortality ratios, effect of smoking
levels, 3840

SMOKERS, PIPE
mortality ratios, 33-43
mortality ratios, effect of smoking
   duration, 3341

mortality ratios, effect of smoking
levels, 33-41

SMOKERS vs. EX-SMOKERS
(See a&o CESSATION OF SMOKING;
  EX-SMOKERS)
annual probablity of dying, 34-37
SMOKERS vs. NONSMOKERS
abruptio pI&?en&, 3, 5-6, 8
annual probability of dying, 34-37
birth weight in offspring, 4
membrane rupture during pregnancy,
   7-3

myocsrdial infarct in oral contracep-
  tive users, 13-15
perinatal mortality, 5
placenta previa, 3-4, 6, 3
prematurity, 4

SMOKING (S% o4.so SMOKE, CIGA-
RETTE; SMOKERS, CIGAR;
SMOKERS, PIPE; SMOKING DU-
RATION; SMOKING LEVELS;
SMOKING, MATERNAL)
effect on blood vessels, 13
effect on carboxyhemoglobin levels
  in pregnant vs,
  nonpregnant women, 11
effect on mortality, 21-45
in etiology of disease, review of
   mechanisms, 47-49
synergistic action in disease etiology,
   49

SMOKING AND HEALTH
research needs, 53-56
SMOKING DURATION
(See ah EX-SMOKERS; SMOKERS,
CIGAR; SMOKERS, PIPE; SMOK-
ING; SMOKING LEVELS)
effect on mortality ratios in cigar
   smokers, 3339

effect on mortality ratios in ciga-
rette smokers, 23-29
effect on mortality ratios in ex-
smokers, 3234


INDEX

effect on mortality ratios in pipe
  smokers, 3&11

SMOKING HABIT
children and adolescents, 50, 52
initiation, establishment, maintenance
   and modification, 50-51
research needs, 53-54,56
trends in 20th Century, 51-53
women, 1

SMOKING LEVELS
(See dao SMOKERS, CIGAR; SMOK-
ERS, PIPE; SMOKING; SMOKING
DURATION; SMOKING LEVELS,
MATERNAL)
effect on mortality ratios in cigar
   smokers, 33-40

effect on mortality ratios in ciga-
rette smokers, 2'7-29
effect on mortality ratios in ex-
smokers, 3234

effect on mortality ratios in pipe
  smokers, 3341

effect on myocardial infarct risk in
   oral contraceptive users, 1415
SMOKING LEVELS, MATERNAL
(Sa aiao SMOKING, MATERNAL)
abruptio placentae and, 3, 5, 7
bleeding during pregnancy and, 3, 7
effect on birth weight, 24
effect on carboxyhemoglobin levels,
   10

effect on intellectual and physical
development in offspring, 3-9
effect on perinatal mortality, 3, 5, 7
membrane rupture during pregnancy
  and, 3, 7

prematurity and, 3-4
placenta previa and, 3-4, 7

SMOKING, MATERNAL
(See aleo SMOKING LEVELS, MATER
  Nfi)
effect on birth weight, l-2
effect on DDT levels in breast milk,
    15

effect on fetal/maternal carboxyhem-
oglobin ratio, 11
effect on intellectual and pbyaical
development in offspring, 3-9
effect on lactation, 15
effect on oxygen transport in fetus
  and mother, 11-12
effect on perinatal mortality, 2-3
effect on pregnancy, 1-13
effect on pregnancy, public aware-
ness, 15-16

effect on umbilical artery, 13
low birth weight and, 13
perinatal mortality and, 13
stillbirths and, 8
STILLBIRTHS
(,See also PERINATAL MORTALITY)
maternal smoking and, 8
THROMBOEMBOLISM
(See also CARDIOVASCULAR DIS-
EASES)
mortality rate in oral contraceptive
   users and smokers, 14
TOBACCO INDUSTRY
effect of advertising on cigarette
   sales, 52-53

UMBILICAL ARTERY
effect of maternal smoking, 13
U.S. VETERANS STUDY
methodology, 26
WOMEN

smoking habit, 1
summary of smoking related health
problems, 17