Here, Luria responds to an inquiry by Pardee, who--along with Francois Jacob and Jacque Monod--had just one year earlier shown that the enzyme beta-galactosidase is induced by changes in culture conditions. It was the first example of negative control of induction due to a repressor protein. This discovery set the stage for additional experiments that further delineated the interaction of a regulatory protein with a site on DNA that controls expression of other genes. With this letter, Luria also enclosed a copy of his 1949 article with Rene Dulbecco.
Number of Image Pages:
1 (53,207 Bytes)
Date:
1960-05-23 (May 23, 1960)
Creator:
Luria, Salvador E.
Recipient:
Pardee, Arthur B.
University of California, Berkeley
Source:
Original Repository: American Philosophical Society. Library. Salvador Luria Papers
Rights:
Reproduced with permission of Daniel D. Luria.
Reproduced with permission of the American Philosophical Society.
Subject:
Medical Subject Headings (MeSH):
Bacteriophages
Exhibit Category:
From Phage to Colicins, 1945-1972
Relation:
Genetic Recombinations Leading to Production of Active Bacteriophage from Ultraviolet Inactivated Bacteriophage Particles (March 1949)