January 30, 19%

Dr. A. Hershey

Carnegie InstZtution of Washington
Dtqxhaent of Genetica
Cold Spring Harbor, Long Island, New York

lhar Al:

I have read your review with great pleasure and, unless you
want it back, I should like to keep it. These are a few
suggestions, as you asked fort

Page 21, lines 7-9.  The erotic induction for Lambda
  should pro&bly be mentioned here.

Page 23, line 6.  I think some original papers on toxin
  production should be quotid rather than J&de&m-g's
  mention.

Page 25, line 10,  The main findings of Charen and Under,
  quoted here and later, should be &ven since otherwise
  this paragraph is nonunderstandable.

Page 25, lim 5 up.  Th5s sentmce is probably s. little
  too deep to be understood.

Page 26, line3 5 up*  It might be worth mentioning that
  in the cam of lambda transduction fs limited to
  phage from lyaogenics.

Page 28,  In the section on gmetics you may want to
mention Cohenis discovery (?) of high glucose content
  in some TZr stocks.

Page 39, lines I.2 and following. You promise an exciting
  description of the experimental decision and then say
  nothing more of it.  fs there a paragraph missing?

Page r;l, lines 3-6.  This is much too mysterious to be
  given tithout explanation.


Page &6, linea 8-4 up,  You should state here thr& this has
been publiplhed only for the phages with I-MC, but ttit you
have confirmd it for T5, afnce the qulestion is very
  important.

P@m 49, line 4.  This ip3 probably a tiestatement. Oross LW
  incmase my stop but you have shown that DNA synthesis
  does not.

Beference.  The paper by French and Siminovitch has not been
  submitted to VW+

Stahl~s paper will appear in the April issue. The associate
editors should begin receivkg Viroloq starting with volume 2.

Finally, T hope yo11 go ahead wjlth the experiment on iNI synthesis
with UV phage,  I doubt whether 1 can do a,@hing of the sort
in the near future,  I am not quite clear a5 to your experimmt
with W in P32 phage.  Do you mean to say that in mixed infection
there is doad phage produced?  Me never found any apprecitable
amount of it, but of course we only had the killing ability to
go on+  If I understand correctly you get an excess of injectable
IA&. over the Bmount accountable for by live phage, This would
mean that on a second transfer experiment you should find much
lass than th% usual sO$,  1s this the first evidence that a dead
phage can mature? Are all of the labels so high that some pcisticles
may die after having been producad?

Hoping to hear more mxmj and with best regards,

Sincerely yours,

S. E. Luria