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The Francis Crick Papers

Title:
Letter from Francis Crick to Aaron Klug pdf (167,363 Bytes) ocr (1,816 Bytes)
Description:
Crick here commented again on the draft of a paper by Klug on the spatial arrangement of DNA and histones (proteins associated with DNA) in nucleosomes, particularly on the dimensions of the DNA helix, whether the DNA helix was itself coiled in a nucleosome (forming a coiled coil, or superhelix), and the number of base pairs per turn of the superhelix. Crick also pointed out that as DNA shrank from its hydrated, elongated B form (or fiber form) to its shorter, drier A form, the X-ray diffraction patterns of DNA in nucleosomes changed in ways that might affect Klug's conclusions.
Number of Image Pages:
2 (167,363 Bytes)
Date:
1977-06-30 (June 30, 1977)
Creator:
Crick, Francis
Recipient:
Klug, Aaron
Source:
Original Repository: Wellcome Library for the History and Understanding of Medicine. Francis Harry Compton Crick Papers
URL: http://archives.wellcome.ac.uk/
Rights:
Reproduced with permission of the Wellcome Library for the History and Understanding of Medicine.
URL: http://library.wellcome.ac.uk/
Subject:
Medical Subject Headings (MeSH):
DNA
Nucleosomes
Crystallography, X-Ray
Exhibit Category:
From Molecular Biology to Neurobiology, 1976-2004
Relation:
Metadata Record Letter from Aaron Klug to Francis Crick (July 18, 1977)
Metadata Record Letter from Francis Crick to Aaron Klug (July 1, 1977)
Metadata Record Letter from Francis Crick to Aaron Klug (June 20, 1977)
Box Number: 23
Folder Number: PP/CRI/D/2/18
Unique Identifier:
SCBBQG
Document Type:
Letters (correspondence)
Language:
English
Format:
application/pdf
image/tif
Physical Condition:
Good
Series: Correspondence
SubSeries: Individual Correspondents
Folder: Correspondence with Aaron Klug
Metadata Last Modified Date:
2004-10-22
U.S. National Library of Medicine, 8600 Rockville Pike, Bethesda, MD 20894
National Institutes of Health, Department of Health & Human Services
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