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The Francis Crick Papers

Title:
Letter from Francis Crick to Aaron Klug pdf (207,592 Bytes) ocr (922 Bytes)
Description:
Crick here commented further on the draft of a paper by Klug on the spatial arrangement of DNA and histones (proteins associated with DNA) in nucleosomes. Particularly, Crick debated the dimensions of the DNA helix in nucleosomes and how the DNA helix was itself coiled in a nucleosome (forming a coiled coil, or superhelix). Nucleosomes have since been determined to consist of eight histone molecules wrapped by a DNA segment of about 150 base pairs in length. Under the electron microscope nucleosomes, which are linked to each other by DNA sequences about fifty base pairs in length, appear as bead-like bodies on a string.
Number of Image Pages:
2 (207,592 Bytes)
Date:
1977-06-20 (June 20, 1977)
Creator:
Crick, Francis
Recipient:
Klug, Aaron
Source:
Original Repository: Wellcome Library for the History and Understanding of Medicine. Francis Harry Compton Crick Papers
URL: http://archives.wellcome.ac.uk/
Rights:
Reproduced with permission of the Wellcome Library for the History and Understanding of Medicine.
URL: http://library.wellcome.ac.uk/
Subject:
Medical Subject Headings (MeSH):
DNA
Nucleosomes
Exhibit Category:
From Molecular Biology to Neurobiology, 1976-2004
Relation:
Metadata Record Letter from Aaron Klug to Francis Crick (July 18, 1977)
Metadata Record Letter from Francis Crick to Aaron Klug (July 1, 1977)
Metadata Record Letter from Francis Crick to Aaron Klug (June 30, 1977)
Box Number: 23
Folder Number: PP/CRI/D/2/18
Unique Identifier:
SCBBQH
Document Type:
Letters (correspondence)
Language:
English
Format:
application/pdf
image/tif
Physical Condition:
Good
Series: Correspondence
SubSeries: Individual Correspondents
Folder: Correspondence with Aaron Klug
Metadata Last Modified Date:
2004-10-22
U.S. National Library of Medicine, 8600 Rockville Pike, Bethesda, MD 20894
National Institutes of Health, Department of Health & Human Services
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