June 20, 3.877 Dr. Aarou Klug, Tt0,R.S. M.R.C. Laboratory of Holacula~ Biology Hiller Wm.d, Carrabridge, 432 2QX Euglartd . f was very glad to get your long latter and the draft of your paper, but f hAd only time before the meeting to study them roughly and, (IS you probably Iward Irma J&n, 1 dmmloped a virus inferct:lon during the aw&ing so that it is only now that I bave had the ogprtunity to gs 0~81: it cam-- fUlly* ?4y only strong criticism is on a ratker drstailced point. As I tuld John, you haw tto wideners at all that the umber of b-e-pairs pew super- hdical turn is lmactlp 3.4 St ctmld just as easiSy be 7% Z/2 ur 82, Evera tlm evidmc% that it is mar 80 ia ww& and Sndiratct, thmgh probblp cm- rect. My main criticism a4 your papen- is that itd wr3tt4m 'histoxically' rather than Pog2crlly. 34 you +t3811y hawe Silqgl~ crystal data for intact Page 2 - Juns 2o;I977