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The Francis Crick Papers

Title:
Letter from Francis Crick to Aaron Klug pdf (478,615 Bytes) ocr (213 Bytes)
Description:
Crick expressed reservations about the evidence used by his two co-authors in support of their idea that chromatids, the one-half of a chromosome that splits off from the other half during cell division, were organized in a hierarchy of helices: the chromatid is a folded and coiled super-solenoid (a long, regular, hollow cylindrical structure), also called the unit fiber, which in turn is formed by a coiled solenoid of smaller diameter, which in turn is formed by coiling the string of nucleosomes, bead-like complexes of DNA and protein.
See Leth Bak, Jesper Zeuthen, and Crick, "Higher-Order Structure of Human Mitotic Chromosomes," Proceedings of the National Academy of Sciences, vol. 74 (April 1977), pp. 1595-99.
Item is a photocopy.
Number of Image Pages:
2 (478,615 Bytes)
Date:
1977-01-17 (January 17, 1977)
Creator:
Crick, Francis
Recipient:
Klug, Aaron
Source:
Original Repository: Wellcome Library for the History and Understanding of Medicine. Francis Harry Compton Crick Papers
URL: http://archives.wellcome.ac.uk/
Rights:
Reproduced with permission of the Wellcome Library for the History and Understanding of Medicine.
URL: http://library.wellcome.ac.uk/
Subject:
Medical Subject Headings (MeSH):
DNA
Chromatids
Exhibit Category:
From Molecular Biology to Neurobiology, 1976-2004
Relation:
Metadata Record Letter from Aaron Klug to Francis Crick (March 11, 1977)
Metadata Record Letter from Aaron Klug to Francis Crick (January 27, 1977)
Metadata Record Higher-Order Structure of Human Mitotic Chromosomes (April 1977)
Box Number: 23
Folder Number: PP/CRI/D/2/18
Unique Identifier:
SCBBQT
Document Type:
Letters (correspondence)
Language:
English
Format:
application/pdf
image/tif
Physical Condition:
Good
Series: Correspondence
SubSeries: Individual Correspondents
Folder: Correspondence with Aaron Klug
Metadata Last Modified Date:
2005-07-06
U.S. National Library of Medicine, 8600 Rockville Pike, Bethesda, MD 20894
National Institutes of Health, Department of Health & Human Services
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