Dr Jiw2ques YIonod ,
rnstit;t P",Steur,
25 Rue du Doctsur ROUX,
l?mis ??? o

Dsar Jacques,

   I have Just had a Zetter from Danny Lshrmxx reminding us that we
ssid we would visit his laboratory when we are both over there in October,
I am still keen to do rt;,hIa.   Are you?   If so 1 think we should try to
arrange Q time otherwfse it may turn out that ths two of US cannot g:o
on ths same day,   The c);viou~~ days are either Tuesday 17th October or
Saturday 2lst October.   Aa far WI 1 am concerned the latter would be
py&mable providiq .y Saturday is a possfble day for iehr~~~   Let me
know what you feel,   I expect Sydney ~~ofI1 aleo come9 but as he is in
the states at the moment I cannot ask him which day is better for him,

  There has been no change fn our plans fm Greece this year.   We
expect to go out about the middle of June and stny there till the end
of July, although I have heard very Uttle from the mm who 3t~ looking
sfter the boat and the snginss.   I think the moot asnsiM,e idea would
be to try to meet at a port in the middle of the Aegean soon after you
have Pfwt Spetsai.   ft might be aansible if we fIxed on a particular
port and the approximate date, although Z think we should have some
other means of keeping Zn touch in case we miss eaoh other,   Which
port do you think would be beat for our rendezvaur?   Z seem to remember
you euggeoted Xoa,

   Sp3ney and the others have some suggestive evidence `that %A
produce8 polypeptide chain ternfnation.   Xn brief, they have a strong
suppre3s3or which 5.3 spsuifio for UGA and using this havs converted two
ochrs mutants in p-galactosidase into WGA and Shown that they have the
fame polar properties a.8 do the ochrs and amber at the same sitea.


-2-

13th April 196'7,

Zipsar has done something similar.   However, we still. JIEtck direct
evi.dencc that UGA chain terminates, and because ft is suppressed so
easfly TM? still think that UAA is the triplet comn.only used for chain
temination.

  I have mde `some progmss on the problem. 09 why proteins aggregate
.wlng dgads.  It is pore complicated than I expected, but at least I
`cm see the remon in a ganoral way,   Probably t-hs best tirce to talk
dmtxt this WCXI~~ be when wt? m@@t fn the sumer.

F,LC, Crick.