4 (21 January 1965) 1, The Ctorgas fkm0rial Xnstitute of Tropical and Preventive &x&in% TheGorgas Fk+xtlorieit Institute of Tropical and Preventive Medicine is a private a,g%ncyincorporated in Delaware. The Institutelaaywell tm unique in that the majori* of the incorporators werY9 officials of a id8nt of Panama, the President of the National Board of Health of Panama, and the Surg%ans Gsnsral of the United States Arapr, kvy, and Public ruwongthe nine incorporators. The inttiatfve for the creation of th% Gorgas fih4morial Institute cam% froa~ Pr%sidentBerliseurio Pc~rras of Panama in1920, only a fewmonths after the death of Go~gas. The Pr%sid%nt of Panama ernvisaged the ~QlT@t3 Memorial as a medical research center associated with the FAnto Tom&s Hospitalinwkkh the nations of the Americas would commemorate the pion8%r sanitary work of General Gcrrgas in Cuba and Panama by cooperati3q in llrtudies leading to the s0lution of their common dieease problems. In reply to a psrsunal letter frost President Forras asking the Surgeon Ckneral of the United States Navy to cooperate in the organisa- ~SOA Of an InStitUt% Of %~pfC&l &xiki~ in Par&a&a to be named for th8 late Surgeon Gen43rald. C. Corgas of the Utited Statsrs Army, Admiral Braisted had writtar II . ..the studyoftmpicalm%dlci.neis ofvitaliqortance t0 the people of Ammica and should be 12rxiertaken by the scientiata of the various republics of this c0ntWt not only with a view to aaviqhumanllfe . ..but also as an indlr8ct m%ans of incrt~asing the harmony and mutual %steem which should prevail a~ng us." 2 The Surgeon General had proposed also that the Chargd d'llffaires of Panama sound out the Department of State, the Fan American Union, and the Foreign Relations Committee of the Senate regarding government aid to the Gorgas Memorial. Nothing is known of any approach to the United States Government at that time looking towards U.S. support of the Gorgas Hemorial Institute. Instead, plans were made to raise an endowment fund of ~,OOO,OOO.OO dol- lars by public subscription to finance the work of the Institute. 2. The Gorgas Memorial Laboratoq The Gorgaa Memotial Laboratory is a research laboratory operated by the Gorgas Memorial Institute of Tropical and Preventive Medicine with resources made available by the governments of the Republic of Panama and of the United States, and by other agencies. Following the incorporation of the Gorgas Memorial Institute in 1921 in the United States, under the laws of the State of Delaware, its charter was registered and legalized in the Republic of Panama. In 1923, the Republic of Panama purchased land for the Gorgas Memorial Laboratory adja- cent to that of the Santo Ton& Hospital3 this site was officially dedicated in February 1923 by the President of Panama for the Gorgas Memorial Labo- ratory, and a marker placed commemorating the act. The attempt to raise an adequate endowment by public subscription failed; in 1928, Representative Maurice H. Thatcher of Kentucky, a member of the Isthmian Canal Commission during the construction period and later Governor of the Canal Zone, introduced a bill (HR 8128) to authorize a permanent annual appropriation for support of the projected Gorgas Memorial Laboratory on the Isthmus of Panama. After due action by the House and the 3 Senate, HR 8128 became Public Law No. 350 (70th Congress) by signature of President Calvin Coolidge on May 7, 1928. Purposes The Committee on Foreign Affairs, in reporting to the Committee of the whole House (House Report No. 706, 70th Congress, 1st Session), gave the twofold purposes of the measure as: "First, to authorize as the contribution of the United States Government thereto a permanent annual appropriation of 50,000 dollars for the maintenance and operation of the Gorgas Memorial Laboratory, on the Isthmus of Panama; and, second, to memorialize in a vital and effective way the name of General kLLlliam Crawford Gorgas, who wrought such miracles of sanitation in Cuba and on the I~thmus.~~ 3. The International Nature of the Gorgas Memorial Laboratory From the beginning in 1921, the Gorgas Memorial Laboratory was planned as an international venture. At the first meeting of the Provi- sional Committee, the President of Panama was declared President and Founder of the Provisional Board of Directors of the Gorgas Memorial Institute; at the second meeting, the Ambassador of Peru and the Ministers of Cuba and Ecuador were made Honorary Members of the Memorial; and at the fourth meeting the Ambassador of Peru, the Ministers of Cuba and Venezuela, and the Charg6 d$Affaires of Argentina were present. After incorporation of the Gorgas Memorial Institute, an approach was made to the Latin American governments through diplomatic channels and through personal visits to the Presidents of several countries. Promising relations were established which could not be developed at the time because of the failure to secure funds in the United States. The commitment of Panama to furnish a site and a building for the Gorgas Memorial Laboratory and the favorable reactions of other nations were reported to the Congress in the hearings on RR 8128. 4 The authorization for a permanent annual contribution to the Gorgas Memorial Institute for the maintenance and operation of the Gorgas Memorial Laboratory was conditional to the construction of the Laboratory building within the next five years, on the site offered by the Republic of Panama, or on a site in the Canal Zone to be provided by the United States. This stipulation was promptly met by the Republic of Panama which deeded to the Gorgas Memorial Institute, in perpetuity, so long as it be used as a research laboratory, the site and building in which the Gorgas Memorial Laboratory has operated since 1929. In 1963 an additional building, financed by the United States Government, was constructed on the same site. The Gorgas Memorial Laboratory was further recogniaed as an inter- national effort by Congress in providing that each of the Latin American governments be invited and permitted to contribute to its maintenance and operation; each contributing Latin American nation was to be represented on the Directing Council of the Gorgas Memorial Laboratory in proportion to its contribution. Inadvertently, this proviso limited the total Latin American representation to 43 per cent, since the Latin American financial contribution was limited by the same act to 75 per cent of the United States contribution. In emphasizing the quasi-official nature of the Gorgas Memorial Labo- ratory, the Congress established permanent United States representation on the Directing Council "in such manner as tie President may determine." (President Hoover declared on December 1, 1930 his satisfaction with the representation of the United States by the Surgeons General of the Army, the Navy, and the Public Health Servicei today's By-Laws provide also for representation by the Surgeon General of the Air Force.) The Congress also requires a full annual report to it by the Gorgas I4emorial Institute on the operation and the work of the Gorgas Memorial Laboratory3 the Comptroller General of the United States audits the accounts of the Gorgas Memorial Laboratory. Thus, the United States Congress, while providing for the participa- tion of other nations, made such participation unattractive by keeping control in the Directing Council and requiring the Gorgaa Memorial Insti- tute to report to the United States Congreats and to have its books audited by the United States Government. Usual usage would have the report made to the Directing Council and the audit made by a nominee of the Council. It may well be that the difficult financial situation in the years following 1929 may have been the determining factor in preventing a greater participation of Latin American nations in the financing of the work of the Gorgas Memorial Laboratory. Thirty-five years later few will remember the impact of the economic crisis on the political life of Latin America; all of the governments of South America suffered upheavals, with the exception of Paraguay and Venezuela. Even in the United States this was a period of severe retrenchment. Fortunately, the Act authorizing a permanent annual appropriation for the maintenance and operation of the Gorgas Memorial Laboratory of Hay 7, 1928 was amended by PL 339 (83rd Congress, 2nd Session) of April 19, lp!j&, making it much more acceptable as the basis for true international collaboration. The stipulations regarding the limitations on and the pro rata nature of contributions and of representation of Latin American nations were rescinded; also rescinded was the stipulation regarding U.S. representation on t,hc iXrect.ini: Council, 6 In their plaue, the following was enacted: n . ..and (2) that the Baid Gorgae Memorial Institute be, and it is hereby, authorized within its discretion, henceforth to acaept from any of the Latin Amerioan Governments, or from any other sourcea, aqy funds which may be offered or given for the use of the Gorgasr Memorial Institute for the maintenance and operation of the Gorgas Memorial Laboratory, and for carrying on the work of said Laboratory wherever deemed by the said Institute to be necessary or desirable." In 1953 (October p), six months before the liberalization of the U.S. legislation relating to Latin American participation, the Bureau of the Budget, considering the Qorgas Memorial Laboratory as a national rather than an international operation, took from the Department of State ard assigned to the Department of Health, Education, and Welfare budgetary responsibility for contributions made by the United States to the Gorgas Hemorial Institute for its support. This move, in effect, denied the continued participation of the Republic of Panama in the Gorgas Memorial Laboratory. This action overlooked entirely the international origin of the Gorgaa Memorial Institute itself and the conditions under which the Gorgas Memo- rial Laboratory was created; viz., the Gorgaar Memorial Institute acted as an intermediary in a non-treaty agreement through which the Governments of Panama and of the United States collaborate through the Gorgaer Memorial Laboratory in researoh on tropical diseases to memorialize for future generations the life and work of General Gorgas. This action also left out of consideration the termsp of the agreement between the Gorgaa Memo- rial Institute ani the Government of Panama under which the Gorgas Memo- rial Laboratory operatee in that Republic. At the time of this action, the State Department made clear its 7 interest in continued support of the Gorgas Memorial Laboratory by the United States; in a letter to the Secretary of Health, Education, and Welfare from the Secretary of State (December 2, 1953) are to be found the following statements: If . ..my purpose in writing is to express the interest of the Depart- ment of State in the oontinued appropriation of funds for the main- tenance of this organization... the Department of State desires to point out that there are involved in this matter important consider- ationra affecting the international relations of this government. "The Laboratory was established as a memorial to a great American, who, because of his major contribution to the realization of the trans.Isthmian Canal, is held in high esteem in Panama. The Canal Zone and the Panamanian Government have drawn freely upon and benefitted greatly from the work of the Laboratory, and the Pana- manian Government always has followed the work and the development of the Laboratory with great interest. "It has manifested this interest in donating to the Laboratory an appropriate building and valuable real estate in its capital city, together with various services. Its Ambassador to the United States, who is an ex-officio Director of the Gorgas Memorial Institute, has indicated to the Department of State on numerous occasions the desire of his Government for the continued maintenance of the Laboratory. The P anamanian view the Laboratory as a signal example of cooperation which benefits both nations and its discontinuance through lack of support would be widely interpreted in Panama as disinterest on the p&t of this`Government in such cooperation. "For these reasons the 'Department of State expects that (a) the independent identity of the Gorgaa Memorial Institute and Laboratory will be maintained, including policy making functions; and (b) because the Department of State has the responsibility for deter- mining the foreign relations aspects of the Laboratory and fnsti- tute, the Public Health Service will consult with the Department concerning requests for annual appropriations and any other legis- lation in connection with the Gorgas Memorial Laboratory." In spite of this letter, the Department of Health, Education, and Welfare unilaterally appointed an ad hoc technical committee to determine whether the United States should continue to support the Gorgas Memorial Institute in its operation of the Gorgas Memorial Laboratory. Fortunately, a possible crisis was averted by the committee's recognition of the value 8 of the scientific work of the Gorgas Memorial Laborat5ry and the future potential of it6 +trategic position. During the past decade the Gorgas Nmorial Laboratory has been mod- ernized in keeping with today's altered research needs; additional quar- ters have been provided in part by the United States and in part from private sourcesj salaries have been increased in line with scientific salaries elsewhere; and new fields of research have been added. The increased operating costs have been paid during the past two years in part from non-recurring private funds. 4. The Eiddle Ammica Research Unit (PIARU) Some years ago, the United States, in spite of its interest in the Gorges Hemrial Laboratory, moved to create its own tropical disease research unit in.Panama. Gn October 16, 1957, the Secretary of the Axmy, the Governor of the Canal Zone, and the Surgeon General of the Public Health Service signed an agreement authorizing the Rational Institutes of Health of the United States Public Health Service (MIH) to establish in the Canal Zone a field party for the study of tr5plcal diseases. This aotion was taken because the Rational Institutes of Health, in collaboration with the Walter Reed Army Institute of Research, the Naval Medical Research Institute, the Research Mvision of the Bureau of Nedi- tine and Surgery of the Department of the Navy, the Research and Develop- ment Division of the Office of the Surgeon General of the Department of the Army, the Canal Zone Government, and possibly other agencies of the Government of the United States, wa8 desirou8 of establishing in the Canal Zone a field research party for the study of tropical diseases. 9 The initial agreement was for a three-year period, with provision for evaluation at the end of the second year to determine whether the project abuld become permanent or not. The action was taken at a time when the Cforgas Memorial Laboratory was struggling to improve its physical Pnstallation8 and its technical staff to meet the demands of modern research, particularly in the tirus field; it was taken three years after the National Institutes of Health became responsible for the defense of the Gorgas Memorial Laboratory budget before the Congress. The pre-empting of collaboration with all of the agencies mentioned by the National lnstftutes of Health came in the face of previous collabo- ration of the United States Army and the United States Navy in tropical disease research with the Gorgas Memorial Laboratory. The field research party was established without due consultation with the State Department since, although located in the Canal Zone under the .American flag, its designation, Middle America Research Unit, declares its international objectives, In accord with the initial agreement, an ad hoc Committee for the Ovaluation of MARU was appointed in 1959. This Committee recommended the continuation of MARU for an indefinite period. Additional recommendations included2 i. That, in tiew of the increarsing anti-united States sentiment in the Republic of Panama, steps be taken to secure the provision of suitable quarters in the Canal Zone for all IQRU personnel; ii. That a joint scientific advisory board for the MARU and the GOIV~S Memorial Labornt,5rv frrML) bn est.nhli shed tm deli neatw RPCIZIR of 10 research interest and maintain productive relation8 between these organizationa; and iii. That the wIH/Pan American Sanitary Bureau (PASB) agreement on MARU be revised. In accord with the recommendation for continuation of MARU, the Secretary of Health, Education, and Welfare requested, in 1960, the con- currence of the Director of the Bureau of the Budget of the designation of the Middle America Research Unit of the National Institutes of Health as a permanent research facility of the Public Health Service. The Bureau of the Budget concurred but assumed that the Secretary of Health, Education, and Welfare would seek the advice of the Department of State with respect to any relevant foreign policy implications of this action. No record of consultation with the Department of State has been found. The recommendation that the personnel of MARU should all be housed in the Canal Zone servers but to emphasize the difficulties encountered by official agencies of one government attempting to operate from a domestic base in other countries. (The succe8s of the Naval Medical Research Units in Egypt and in Taiwan has been possible because these units were established in the countries concerned under agreements with those countries, There is no c5rresponding agreement with Panama and the other countries of Middle America covering MARU.) In contrast to the MARU staff, the staff of the Gorgas I4em5rial. Laboratory live in the Republic of Panama; they and the Laboratory itself were not molested during the anti-United States riots a year ago. The proposal for a joint advisory board for MARU and GML brings into the open the difficulties of coexistence of the two agencies. 11 Although it has been repeatedly declared that there is no conflict in the programs of MARU and the Gorgas Memorial Laboratory, it is obvious that the HARU program is in conflict with what that of the Gorgas I4emorial Laboratory should be. The creation of a situation which led the Government of Panama to reserve the field of medical research in the Darien region for the Gorgas Memorial Laboratory is certainly not a healthy one. Cbviously, the exist- ence of PIllRU has complicated the relations between the Republic of Panama and the United States. Panama views the Gorgas Memorial Laboratory as part of the national scenery, an agency staffed in part by Panamanian scientists, and views MARU as unwarranted intrusion. The masons for the proposed revision of the NIH/PASB agreement are not apparent in the Committee's report; but it is obvious that MARU could operate more easily outside of the Canal Zone under the banner of the Pan American Sanitary Bureau than under the flag of the United States. 5. The Present Situation in Panama The present situation merits an objective analysis. Such an analysis will show: i. That MARU exists as a 100 per cent United States operation, based in the Canal Zone over which the Republic of Panama cl&m3 sovereignty; ii. That MARU is limited to the Canal Zone except in so far as it operates through diplomatic channels, through the GML, or through the PASB; iii. That the Gorgas Memorial Laboratory now has the potential for becoming a powerful center of medical research and training in the Ameri- can tropics; iv. That this potential is based on: 12 a) The charter of the Gorgas Memorial Institute of Tropical and Preventive Medicine, issued by the State of Delaware, duly registered and legalized in the Republio of Panama, establishes the functions of the Sorgas Memorial Institute as followsl nTo conduct, assist and encourage investigations in the sciences and arts of hygiene, medicine and surgery and allied subjects, in the nature and causes of disease and the methods of its prevention and treatment, and to make knowledge relating to these various subjects available for the protection of the health of the public and the improved treatment of disease and injury, particularly as applied to Tropical and Preventive Medicine. It shall be within the purposes of this corporation to use any means to those ends which from time to time shall seem to it expedient, including research, publication, educa- tion, the establishment and maintenance of charitable or benev- olent activities, agencies or institutions appropriate thereto, and the aid of any other such activities, agencies or institu- tions already established or which may hereafter be established. "The corporation shall have the power to acquire by grant, gift, purchase, devise or bequest, either absolutely or in trust, and to hold, mortgage, convey and dispose of such property, real or personal, situated or being within or without the State of Delaware, as the purposes of the corporation shall require, withovt limitation as to amount, location or Value; to accept and administer any trust of property, real or personal, wherever situated, for any purpose within the objects of the corporation; and to prescribe by by-laws or otherwise the term and conditions upon which property, real or personal, shall be acquired or received by the said corporation. 'The corporation shall also have power to build, purchase, improve, enlarge, equip and maintain laboratories and other buildings within the Republic of Panama and elsewhere necessary or appropriate for its work; to own and operate land and build- ings for the breeding, raising and keeping of plants and ani- mals to be used for its purposes; to furnish treatment for diseases of man and of animals, and to provide and maintain all necessary equipment therefor; to conduct and assist such scientific experiments or investigations upon plants or animal8 as may be necessary or proper for carrying on its work of research; to appoint committees of experts to direct special lines of research; to aid, cooperate with, or endow other asso- ciations or corporations engaged in similar work within the Republic of Panama or elsewhere; to aid and cooperate with investigators in its own laboratories or elsewhere; to collect statistics and information, and to publish and distribute 13 doouments, reports and periodicals; to carry on such educa- tional work along the lines of its corporate purposes as it may deem wise; to provide for and furnish public instruction in hygiene, sanitation, and laws of health; to conduct lectures and hold meetings; to acquire and maintain a library; to erect and maintain museums; and in general to do and per- form all things necessary or convenient for the promotion and the objects of corporation or aw of them. "To have offices, plants and places for carrying on and conduct- ing its affairs and for fulfilling the objects of its organiza- tion, outside of the State of Delaware, and to carry on its business and affairs and to promote its objects without restric- tions as to place or amount. "To do any or all of the things herein set forth to the same extent as natural persons might or oould do and in any part of the world, as principals, agents, contractors, trustees or otherwise, alone or in company with others." b) The specific authorization in PL 339 of the 831-d Congress, amending PL 350 of the 70th Congress, which reads as follows: N . ..and (2) that the said Gorgas Memorial Institute be, or it hereby is, authorized within its discretion, henceforth to accept from any of the Latin American Governments, or from airy other sources, any funds which may be offered or given for the use of the Gorgas 24emorial Institute for the mainte- nance and operation of the Gorgas Namorial Laboratory, and for carrying on the work of said Laboratory wherever deemed by the said Institute to be necessary or desirable." c) Thirty-five years of peaceful cooperation with the authori- ties and people of Panama with the development of an international staff. d) Recently constructed modern laboratory facilities a& insectary. e) Access to the wards of the Santa Tom& Hospital and to a number of beds specifically reserved for patients studied at the Gorgas Memorial Laboratory. f) A fully qualified Director and the nucleus of a well quali- fied scientific staff experienced in tropical disease study and adapted g) Its strategi c 1 ocation on the Isthmus at a time when the southward extension of the Pan American Highway and plans for a new trans-Isthmian Canal emphasize the importance of continuing study of tropical diseases. h) The cooperation of the six countries of the Isthmus during the past 15 years in the Institute of Nutrition of Central America and Panama (INCAP), which should make it relatively easy to develop similar multi-nation participation in research in tropical diseases through the Gorgas Memorial Laboratory already located in the region. i) The facility of the Gorgas Memorial Institute, as a private corporation, to work with governments of many countries in the manner developed by the Rockefeller Foundation during its studies on and control of yellow fever. It 18 obvious that there is need for research beyond the capacity of both MARU and the GML; it seems likely that a better situation might exist today had the United States found a way to channel the resources poured into MARU since 195'7 into the earlier development of the GML. Today there is every reason for the Gorgas Memorial Institute to take the leadership in developing greater participation of the Republic of Panama and of the United States in the development of the Gorgas Memorial Laboratory, in such a way as to facilitate the participation of the National Institutes of Health and other United States agencies in tropical disease research while at the same time opening up neighboring countries for necessary expansion of the field of operations.