July 5, 1960 Dr. Van R. Potter Mc Ardle Memoria 1 La bora tory The University of Wisconsin rhe Medical School Madison 6, Wisconsin Dear Van: It was very kind of yoa to send me your latest modification of the DNA model. I have had a chance to study it and play with it a little. connections, I find it awkward to use the models for instructional pur- poses. usefulness to the average student to warrant the extra expense and complication. keep the double strand together fix the model in such a way that single nucleotide units cannot be put in or taken out. While it is a most ingenious way of showing the hydrogen bond I seriously doubt that these modifications will be of sufficient Another limitation is the fact that the two wires which I'd like to tell you again how popular and valuable the models were in our general biochemistry course. tide pairs gratia and invited those who wished to build a large-scale model to buy their own. a class of about one hundred. We distributed four nucleo- On this basis, we sold fifty or more models to With warmest regards, Sincerely yours, Arthur Kornberg AK: e 8