Captopril: Evaluation of Low Doses, Twice-Daily Doses and the Addition of Diuretic for the Treatment of Mild to Moderate Hypertension
Description:
In the early 1980s, a new class of drugs were developed that treated hypertension by preventing the synthesis of certain hormones that caused blood vessels to constrict. These drugs, of which Captopril was one, were designated as angiotensin converting enzyme (ACE) inhibitors. Freis's team reported that Captopril, which up to then had only been administered to the most severe hypertensive patients, effectively reduced blood pressure in lower doses than indicated in previous studies, reducing the likelihood of deleterious side effects. As a result, they recommended that its use be extended to the general population.
Number of Image Pages:
3 (379,966 Bytes)
Date:
1982
Creator:
Veterans Administration Cooperative Study Group on Antihypertensive Agents
Source:
Periodical: Veterans Administration Cooperative Study Group on Antihypertensive Agents. "Captopril: Evaluation of Low Doses, Twice-Daily Doses and the Addition of Diuretic for the Treatment of Mild to Moderate Hypertension." Clinical Science 63, (1982): 443s-445s. Article. 3 Images.
Publisher:
[Medical Research Society]
Rights:
This item is in the public domain. It may be used without permission.
Subject:
Medical Subject Headings (MeSH):
Hypertension
Antihypertensive Agents
Captopril
Hydrochlorothiazide
Exhibit Category:
After 1980: Changing Trends in Hypertension Therapy
