Effect of Pentaquine in Patients with Hypertension
Description:
Following World War II, Freis returned to Boston to work with Wilkins at Massachusetts Memorial Hospital. Their work on pentaquine was an outgrowth of anti-malarial work conducted by others during the war, in which it was observed that some volunteers developed orthostatic hypotension. In this article, they report that the drug did lower blood pressure, yet it would not be an effective antihypertensive agent because it also produced severe toxic effects.
Item is a photocopy.
Number of Image Pages:
4 (382,962 Bytes)
Date:
1947
Creator:
Freis, Edward D.
Wilkins, Robert W.
Source:
Periodical: Freis, Edward D., and Robert W. Wilkins. "Effect of Pentaquine in Patients with Hypertension." Proceedings of the Society for Experimental Biology and Medicine 64, (1947): 455-458. Article.
Publisher:
Society for Experimental Biology and Medicine
Rights:
Reproduced with permission of the Society for Experimental Biology and Medicine.
Subject:
Medical Subject Headings (MeSH):
Hypertension
Antihypertensive Agents
Aminoquinolines
Exhibit Category:
Early Career and Work with Antihypertensive Drugs, 1940-1949
