The Edward D. Freis Papers

Title:

Effects of Treatment on Morbidity in Hypertension: Results in Patients with Diastolic Blood Pressures Averaging 115 through 129 mm Hg

Description:

The first of three publications describing the results of the Veterans Administration Cooperative Study on Antihypertensive Agents. This is the work for which Freis received the Lasker Award. For this double-blind study, some patients presenting with severe hypertension at VA Hospitals were administered a regimen of several antihypertensive agents. Patients were excluded if they had curable forms of hypertension. Due to a tremendous difference in morbidity and mortality between control and treated patients, the study was terminated after only 18 months for a subgroup of patients that originally had an average diastolic blood pressure of 155 through 129 mm Hg.

Number of Image Pages:

7 (1,082,670 Bytes)

Date:

1967-12-11 (December 11, 1967)

Creator:

Veterans Administration Cooperative Study Group on Antihypertensive Agents

Source:

Periodical: Veterans Administration Cooperative Study Group on Antihypertensive Agents. "Effects of Treatment on Morbidity in Hypertension: Results in Patients with Diastolic Blood Pressures Averaging 115 through 129 mm Hg." Journal of the American Medical Association 202, 11 (11 December 1967): 1028-1034. Article. 7 Images.

Publisher:

American Medical Association

Rights:

This item is in the public domain. It may be used without permission.

Subject:

Medical Subject Headings (MeSH):: Hypertension; Antihypertensive Agents; Blood Pressure

Exhibit Category:

The VA Cooperative Study and the Beginning of Routine Hypertension Screening, 1964-1980

Relation:

Effects of Treatment on Morbidity in Hypertension: II. Results in Patients with Diastolic Blood Pressure Averaging 90 through 114 mm Hg (August 17, 1970)

Effects of Treatment on Morbidity in Hypertension: III. Influence of Age, Diastolic Pressure, and Prior Cardiovascular Disease; Further Analysis of Side Effects (May 1972)

Effect of Treatment on Morbidity in Hypertension. Veterans Administration Cooperative Study on Antihypertensive Agents: Effect on the Electrocardiogram (September 1973)

Rebuttal: Appraisal of Antihypertensive Drug Therapy (July 1974)

Box Number: 7