According to Avery's colleague and biographer, Rene Dubos, Griffith's findings in this article were like "exploding
a bombshell in the field of pneumococcal immunology." In it, he described his observation of an experiment in which R
cells of type I pneumococcus transformed into S cells of type II in the course of his experiment. Griffith's findings
here were highly influential on several members of Avery's lab, including Martin Dawson and Lionel Alloway. This article
was originally published in January 1928.
Number of Image Pages:
48 (5,132,306 Bytes)
Periodical: Griffith, Fred. "The Significance of Pneumococcal Types." Journal of Hygiene 64, 2 (1966): 129-175. Article. 48 Images.
Cambridge University Press
Reproduced with the permission of Cambridge University Press. Any reproduction or copying of this material in any format,
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Medical Subject Headings (MeSH):
Shifting Focus: Early Work on Bacterial Transformation, 1928-1940
The Transformation of Pneumococcal Types: I. The Conversion of R Forms of Pneumococcus into S Forms of the Homologous Type
[and] II. The Interconvertibility of Type-Specific S Pneumococci (January 1, 1930)
The Transformation In Vitro of R Pneumococci into S Forms of Different Specific Types by the Use of Filtered Pneumococcus
Extracts (January 1, 1932)
Node: Frederick Griffith died in London Blitz April 1941, aet. 60.
See Lancet 5/3/41 (p.588-589 for obit. Also
U DOWNIE, AW
TI PNEUMOCOCCAL TRANSFORMATION - BACKWARD VIEW - FOURTH GRIFFITH
SO JOURNAL OF GENERAL MICROBIOLOGY
VL 73: 1 - & ; 1972;