Skip to main contentU.S. National Library of MedicineU.S. National Library of Medicine


Profiles in Science
   
Pinterest badge Follow Profiles in Science on Pinterest!

The Joshua Lederberg Papers

Title:
Letter from Joshua Lederberg to C. Phillip Miller pdf (57,324 Bytes) transcript of pdf
Letter from Joshua Lederberg to C. Phillip Miller
Number of Image Pages:
1 (57,324 Bytes)
Date:
1951-02-20 (February 20, 1951)
Creator:
Lederberg, Joshua
Recipient:
Miller, C. Phillip
Rights:
This item is in the public domain. It may be used without permission.
Subject:
Medical Subject Headings (MeSH):
Escherichia coli
Bacterial Toxins
Relation:
Lederberg Grouping: Correspondence B
Box Number: 7
Folder Number: 198
Unique Identifier:
BBAAXP
Accession Number:
2
Document Type:
Letters (correspondence)
Language:
English
Format:
application/pdf
image/tif
Physical Condition:
Good
Series: Correspondence, 1935-2002
SubSeries: 1947-1953
Folder: Miller, C. Phillip
Transcript:
February 20, 1951.
Dear Doctor Miller-
I certainly enjoyed my visit with Miss Bohnhoff, your colleagues, and yourself, and am sorry only that time was so short.
We are quite ready to begin plowing through some of the E. coli material from your mice that you referred to in our talk. Aside from the routine isolations from feces, I wonder whether you have picked up any more or less virulent E. coli from the irradiated animals.
As I mentioned, N-12 seems to be remarkably toxic, and I have been losing a goodly number of my rabbits with IV doses of 10 9-10 10 cells. I would like to follow this up somewhat, especially as some of the other strains to which K-12 can be crossed do not appear to be nearly so toxic. Can you suggest a more convenient test system?
Our tests for crossability with K-12 are usually carried out in groups of 20 strains, so that this would be the most convenient unit, on our part at least.
Yours sincerely,
Joshua Lederberg,
Associate Professor of Genetics
Metadata Last Modified Date:
2008-05-27
Linked Data:
RDF/XML     JSON     JSON-LD     N3/Turtle     N-Triples