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The Joshua Lederberg Papers

Title:
Detection of Biochemical Mutants of Microorganisms Annotation pdf (161,360 Bytes) ocr (4,570 Bytes)
Detection of Biochemical Mutants of Microorganisms
Number of Image Pages:
2 (161,360 Bytes)
Date:
1946-09 (September 1946)
Creator:
Lederberg, Joshua
Tatum, Edward L.
Source:
Periodical: Lederberg, Joshua, and Edward L. Tatum. "Detection of Biochemical Mutants of Microorganisms." Journal of Biological Chemistry 165, 1 (September 1946): 381-382. Article. 2 Images.
Lederberg UI: P3
Publisher:
Waverly Press Inc.
Rights:
Reproduced with permission of Joshua Lederberg.
Subject:
Medical Subject Headings (MeSH):
Mutation
Genes
Relation:
Lederberg Grouping: Published Scientific Article
Box Number: 79
Folder Number: 3
Unique Identifier:
BBABEM
Accession Number:
3
Document Type:
Articles
Language:
English
Format:
application/pdf
image/tif
Physical Condition:
Good
Series: Writings
SubSeries: Published Scientific Articles
Folder: P3: "Detection of Biochemical Mutants of Microorganisms" (1946)
Metadata Last Modified Date:
2006-03-06
Linked Data:
RDF/XML     JSON     JSON-LD     N3/Turtle     N-Triples

Annotation by Joshua Lederberg:
KW: delayed enrichment; liminal enrichment; auxotrophs;

How to find straws in a pile of needles!

small colonies, or late-appearing colonies.

early in a series of methodological forays to avert picking thousands
of colonies in quest for mutants.  Superseded by penicillin method
(P-15) and replica-plating (P-27). -- and eventually with far moe efficient
mutagenesis, transposon, etc.

jl 7/16/98