Skip to main contentU.S. National Library of MedicineU.S. National Library of Medicine


Profiles in Science
   
Pinterest badge Follow Profiles in Science on Pinterest!

The Joshua Lederberg Papers

Title:
Letter from Kenneth A. Bisset to Joshua Lederberg pdf (135,328 Bytes) transcript of pdf
Letter from Kenneth A. Bisset to Joshua Lederberg
Description:
Item is handwritten.
Number of Image Pages:
3 (135,328 Bytes)
Date:
1948-09-20 (September 20, 1948)
Creator:
Bisset, Kenneth A.
University of Birmingham (England)
Recipient:
Lederberg, Joshua
Rights:
Reproduced with permission of the University of Birmingham (England).
Relation:
Lederberg Grouping: Correspondence B
Box Number: 6
Folder Number: 131
Unique Identifier:
BBACLC
Accession Number:
5
Document Type:
Letters (correspondence)
Language:
English
Format:
application/pdf
image/tif
Physical Condition:
Good
Series: Correspondence, 1935-2002
SubSeries: 1947-1953
Folder: Bisset, Kenneth A.
Transcript:
20th Sept. 1948
Dear Professor Lederberg,
Thank you for your interesting letter. I enclose reprints of two cytological papers, and will send you others as they become available.
I have not seen anything exactly as you describe it, but have observed a scheme of chromosome rearrangement of which I enclose a diagram:--3,4,5 are a normal division (I am now of the opinion that bacterial chromosomes are always paired. 6 is a tri-nucleate cell which may arise by a reductive division.
[END PAGE ONE]
[BEGIN PAGE TWO]
7 is a fusion nucleus. 8 is the same after a single chromosome doubling. 9,10 are reassortment and chromosome doubling again, followed by 11, fragmentation and return to the bacillary state. This certainly occurs in Rough and Smooth types of Enbacteria, in streps and in Myxobacteria. It has nothing to do with sporing. One paper on this phenomenon should be appearing in the next number of the J. Gen. Microbiol., and one in the J. Hyg. Camb. the latter rather later and fuller.
This scheme leaves room, of course, for a lot of details, conjugation, reduction etc. which I cannot claim more definitely so far.
Yours Sincerely,
K. A. Bisset
Metadata Last Modified Date:
2008-10-10
Linked Data:
RDF/XML     JSON     JSON-LD     N3/Turtle     N-Triples