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The Joshua Lederberg Papers

Title:
Letter from Ernest Borek to Joshua Lederberg pdf (122,444 Bytes) transcript of pdf
Letter from Ernest Borek to Joshua Lederberg
Description:
Item is handwritten.
Number of Image Pages:
2 (122,444 Bytes)
Date:
1956
Creator:
Borek, Ernest
Recipient:
Lederberg, Joshua
Rights:
Reproduced with permission of Deborah Ann Borek.
Relation:
Lederberg Grouping: Correspondence C
Box Number: 9
Folder Number: 67
Unique Identifier:
BBACPH
Accession Number:
5
Document Type:
Letters (correspondence)
Language:
English
Format:
application/pdf
image/tif
Physical Condition:
Good
Series: Correspondence, 1935-2002
SubSeries: 1953-1960
Folder: Borek, Ernest
Transcript:
Dear Dr. Lederberg:
Yesterday we shipped to you a slant of E. Coli K12-J-2-1. We grow it on the Grey and Tatum salt solution supplemented with 50 g/ml of L-Histidine.
It contains enough [Beta]-D-glactosidase to liberate 350 [ . . . ] of o-nitrophenol per hour by a sonicate containing, originally, 10 to the eighth cells/ml.
However, I emphasize again, that the bug does not grow on lactose, nor does it adapt to it.
[END PAGE ONE]
[BEGIN PAGE TWO]
but prolonged incubation with lactose--18 hours--growth begins but this is due to the extra cellular splitting of lactose by the oozed out enzyme of the dead cells. We call the phenomenon-among ourselves--necrobiosis.
I have not published any of this stuff since I felt a genetic study of the bug is sine qua non for any report and this I was not ready to do.
Yours cordially
Ernest Borek
Metadata Last Modified Date:
2005-06-20
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