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The Joshua Lederberg Papers

Title:
Letter from Norman H. Giles to Joshua Lederberg pdf (136,899 Bytes) transcript of pdf
Letter from Norman H. Giles to Joshua Lederberg
Description:
Item is handwritten.
Number of Image Pages:
2 (136,899 Bytes)
Date:
1947-11-17 (November 17, 1947)
Creator:
Giles, Norman H.
Recipient:
Lederberg, Joshua
Rights:
Reproduced with permission of Norman H. Giles.
Relation:
Lederberg Grouping: Correspondence B
Box Number: 7
Folder Number: 38
Unique Identifier:
BBADVK
Accession Number:
8
Document Type:
Letters (correspondence)
Language:
English
Format:
application/pdf
image/tif
Physical Condition:
Good
Series: Correspondence, 1935-2002
SubSeries: 1947-1953
Folder: Giles, Norman H.
Transcript:
Nov. 17, 1947
Dear Joshua,
Thanks for your recent letter. I have been intending to write to you for sometime--and this has provided the necessary stimulus. First, I wanted to tell both you and Esther how happy I was to hear the news of your accepting the position at Wisconsin. I certainly agree that it is a fine opportunity--and I feel that you very definitely did the right thing. Naturally, I shall be looking forward to hearing more about how things are going along when I see you in Chicago.
The formula you sent along is quite interesting and does agree quite well with out general results, though the calculation of the survival rate (in terms of mutant[?] nuclei) using microcondria presents a difficult problem. I have obtained additional data giving a dosage-mutation curve with UV for [...] colonials which agreed with your calculations in terms of several, rather than only one, mutation rate. We have also obtained some suggestive results on different (reversion) mutation rates of independently obtained, though apparently alike, [...] mutants. But we still have problems in attempting to get satisfactory
[END PAGE ONE]
[BEGIN PAGE TWO]
microcondrial stocks (especially in the colonial) for use in further tests. This latter difficulty I am sure Esther will appreciate. You can tell Esther also that the reversion article has been accepted for publication--the A. for B. And will be out before too long, I hope.
Our transcentric mutation work is progressing nicely, though there are so many things to do that it is hard to find time for everything. I am going to Boston and New Haven this week and early next week to make some confirmations cyclotron neutron measurements. Naturally I am looking forward to the opportunity of seeing all my Yale friends again.
Thanks again for your letter, and also the recently-arrived reprint. Best regards to both of you.
Sincerely,
Norman Giles, Jr.
Metadata Last Modified Date:
2008-07-30
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