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The Joshua Lederberg Papers

Title:
Letter from Sam Granick to Joshua Lederberg pdf (82,811 Bytes) transcript of pdf
Letter from Sam Granick to Joshua Lederberg
Description:
Item is handwritten.
Number of Image Pages:
2 (82,811 Bytes)
Date:
1952-11-11 (November 11, 1952)
Creator:
Granick, Sam
Recipient:
Lederberg, Joshua
Rights:
Reproduced with permission of Joel L. Granick.
Relation:
Lederberg Grouping: Correspondence B
Box Number: 7
Folder Number: 50
Unique Identifier:
BBADXG
Accession Number:
8
Document Type:
Letters (correspondence)
Language:
English
Format:
application/pdf
image/tif
Physical Condition:
Good
Series: Correspondence, 1935-2002
SubSeries: 1947-1953
Folder: Granick, Sam
Transcript:
Nov. 11, 1952
Dear Dr. Lederberg:
I wonder whether it would be possible for me to obtain strains of K12. I would like to use them to attempt to prepare mutants by the penicillin[?] method--mutants connected with [...] synthesis.
I would rather start with a sexual organism if possible and that is why I have thought of your K12 strain. I am told however that there's the added complication of prophage. Do you have any K12 free of prophage? Or does that make any difference in growth.
For [...] mutants it would be ideal to start with a highly aerobic, rapidly respiring bacterium--on the assumption that the more actively respiring ones have more [...] enzymes. Does your K12 use up lots of O2 under aerobic conditions? Could one use the
[END PAGE ONE]
[BEGIN PAGE TWO]
penicillin technique on some other actively aerobic bacterium--other than B. coli?
I shall be gratified for any advice and suggestions you may have.
Cordially
S. Granick
Metadata Last Modified Date:
2008-07-30
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