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Very many thanks for your letter and most interesting reprint which adds another viewpoint and new information to a complicated
subject. I enclose the reprint you ask for.
One of my objects in publishing in 1949 was to provoke thought and discussion on whether the explanation of cancerous growth
required the assumption of a stimulus to account for continuous cell division. I favoured such an assumption. But I know
that many general biologists do not. They think there has been a removal of restraints, that is to say that unless restrained
any living cell will divide perpetually given adequate conditions for nutrition. Some work that may reconcile both viewpoints
is coming along, perhaps. You will find a reference that may interest you in a short comment in the Lancet 1952 Vol II, 73,
in a leading article on New Ideas in Cancer Research para. 3 on p. 74.
As you are interested in the subject of
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autonomous growth, I wonder if you would not consider investigating a plant tumour virus which infects Nicotiana. You will
find previous work under P.R. White (Princeton) from 1939 onwards, [...] with A.C. Braun. It would be interesting to know
the chemical products of the multiplication of this virus.