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The Joshua Lederberg Papers

Title:
Letter from Tetsuo Iino to Joshua and Esther Lederberg pdf (60,944 Bytes) transcript of pdf
Letter from Tetsuo Iino to Joshua and Esther Lederberg
Description:
Item is handwritten.
Number of Image Pages:
1 (60,944 Bytes)
Date:
1958-06-01 (June 1, 1958)
Creator:
Iino, Tetsuo
Recipient:
Lederberg, Esther
Lederberg, Joshua
Rights:
Reproduced with permission of Tetsuo Iino.
Relation:
Lederberg Grouping: Correspondence C
Box Number: 11
Folder Number: 77
Unique Identifier:
BBAJQC
Accession Number:
16
Document Type:
Letters (correspondence)
Language:
English
Format:
application/pdf
image/tif
Physical Condition:
Good
Series: Correspondence, 1935-2002
SubSeries: 1953-1960
Folder: Iino, Tetsuo
Transcript:
June 1, 1958
Dear Josh and Esther,
I enclose two pictures of Dr. Ryan. They were taken at his apartment room.
I found the culture of SW577 (described as 90% curly) changes phase between curly and normal. That is, the culture is curly in phase 1 (i) and normal in phase 2 (1.2). The strain seems to be a mutant of H1-Ah1 region. The detailed genetic analysis is in progress. As Dr. Kerridge in this lab has found, the replacement of p-phenylalanin by p-fluro phenylalanin at the regeneration of flagella in phenylalanin requiring mutants of T142 + SW1061 causes the production of curly flagella. If the similar mechanism is involved in the curl in SW577, the strain might have a modified ability to incorporate a specific amino acid into H1-protein.
Best regards to the people in the lab.
Sincerely yours
Tetsuo Iino
Metadata Last Modified Date:
2011-08-15
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