Please excuse my slow correspondence. First of all, I would like to express my gratitude for your kind suggestions and corrections
made for my manuscript on Galactose metabolizing enzymes of E. coli.
Since I have done the analysis of enzyme on the strains which I brought from Woods Hole, I have been involved in a different
problem: that is, the inhibition of growth of E. coli by galactose or possibly galactose-1-phosphate. I did not have a chance
to analyze the enzymes of new mutants which you kindly sent me yet. I also did not have time to accumulate enough cases to
say the level of enzymes quantitatively. Now we are in the process of moving from one floor to the other and I don't
expect to be able to settled for down for a while. But I still keep those quantitative analysis of enzymes in my mind and
hope to be able to do before too long.
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As to the inhibition of growth of E. coli by galactose, I can say at least that transferaseless mutants accumulate Gal-1-P
when they are grown in galactose complete media and that they grow much slowly when they are inoculated into glucose synthetic
media to which galactose also was added, compared to the growth in glucose synthetic media without addition of galactose.
This work is being carried out with Albert Wahla and we are trying to find out the real factor which is inhibiting growth.
Whenever I have obtained more data, I shall write to you.
If you kindly send me the reprints of your recent article in Genetics, I shall appreciate it very much.