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The Joshua Lederberg Papers

Title:
Letter from Joshua Lederberg to Ruth Sager pdf (48,196 Bytes) transcript of pdf
Letter from Joshua Lederberg to Ruth Sager
Number of Image Pages:
1 (48,196 Bytes)
Date:
1957-12-13 (December 13, 1957)
Creator:
Lederberg, Joshua
Recipient:
Sager, Ruth
Rights:
This item is in the public domain. It may be used without permission.
Relation:
Lederberg Grouping: Correspondence C
Box Number: 13
Folder Number: 143
Unique Identifier:
BBAMCV
Accession Number:
19
Document Type:
Letters (correspondence)
Language:
English
Format:
application/pdf
image/tif
Physical Condition:
Good
Series: Correspondence, 1935-2002
SubSeries: 1953-1960
Folder: Sager, Ruth
Transcript:
December 13, 1957
Dear Ruth:
I'm not sure I remember what you wrote about - perhaps it was this. A matroclinous type of inheritance does not rule out chromosomal determination. Your zygote just might not get a certain chromosome from one parent, and double up on the other one, something like "sex ratio" in Drosophila, though here the mt chromosome does not control its own behavior, but that of another one. Sciara would be another precedent for selective elimination of chromosomes.
I don't know how you can rule out this class of hypotheses - an anomalous mechanics for a chromosome can probably be devised to match any plasmid.
Yours sincerely,
Joshua Lederberg
Metadata Last Modified Date:
2008-06-06
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