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The Joshua Lederberg Papers

Title:
Letter from Edward L. Tatum to George W. Beadle Annotation pdf (117,937 Bytes) transcript of pdf
Letter from Edward L. Tatum to George W. Beadle
Description:
Item is handwritten. Item is a photocopy.
Number of Image Pages:
2 (117,937 Bytes)
Date:
1946-07-19 (July 19, 1946)
Creator:
Tatum, Edward L.
Recipient:
Beadle, George W.
Source:
Original Repository: California Institute of Technology. Archives. George Beadle Papers
Rights:
Reproduced with permission of Margaret (Tatum) Easter & Barbara Tatum.
Relation:
Lederberg Grouping: Correspondence A
Metadata Record Letter from Mark Herbst to Joshua Lederberg (June 28, 1981) pdf (43,231 Bytes) ocr (676 Bytes)
/ps/access/BBAPDP.pdf
Box Number: 6
Folder Number: 6
Unique Identifier:
BBAPDS
Accession Number:
14
Document Type:
Letters (correspondence)
Language:
English
Format:
application/pdf
image/tif
Physical Condition:
Good
Series: Correspondence, 1935-2002
SubSeries: 1925-1947
Folder: Beadle, George W.
Transcript:
July 19, 1946
Dear Beets:
Thanks much for the reprint -- and for the tryptophane etc. cultures.
We've been running into a little difficulty in interpreting some of the morphological types coming from no treatment, or after mustard or especially methyl-cholanthrene treatment. These fall into 3 main types, flat, pink-fluffy, and [ . . . ] -- and reach approximately 10 percent of the isolates from 25a x 1A. Has any track been kept of these types from the Stanford isolates? Were planning on using inorganic stocks when theyre [sic] made.
2ndly -- S-mutants (cystine and methionine) have run close to 25 percent of the total biochemicals from mustard. Is that what the radiation isolates ran. Did Norm find a disproportionate number with mustard gas?
3rdly -- To the best of my knowledge, no [ . . . ] biochemicals have come from untreated stocks -- i.e. spontaneous -- in N -- is that still true? We've done close to 2,000 isolates with no treatment, or ineffective treatment, without getting one.
[END PAGE ONE]
[BEGIN PAGE TWO]
The C.S.H. symposium was very fine -- lots of good discussions and some excellent papers -- especially Spiegelman's and Sonneborne's, and Hershey's. Dave did a very creditable job too. Sonneborne has just hind[?] v. Wagtendonk, but you probably already know that.
Dave and Miriam are getting well settled, but are having trouble finding a house for later this summer. The situation is difficult -- except for veterans. I was glad to hear your house in P.A. went to Art (who will appreciate it) and that you are located in Pasadena. How are the rest of the gang making out?
With best regards to all
Yours
Ed
P.S. We recently turned up a N-mustard adinene-purple -- we'd like to know if its [sic] the same as the Stanford purple -- shall I send it on?
Metadata Last Modified Date:
2017-06-19
Linked Data:
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Annotation by Joshua Lederberg:
KW:  thanks for reprint, trp cultures;  morph mutants from mustard; methylcholanthrene;
many cys, met mutants; zero from sponatenous controls; "The CSH symposium
was very fine. good discussions .. Spiegelman, Sonneborn, Hershey,;
Dave [Bonner]; van Wagtendonk; "your home in PA went to Art [perhaps
Giese?];

!! no mention of E coli recombination;

jl  9/11/99
..