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The Joshua Lederberg Papers

Title:
Letter from Edward M. Johnson to Joshua Lederberg pdf (98,140 Bytes) transcript of pdf
Letter from Edward M. Johnson to Joshua Lederberg
Description:
Item is handwritten.
Number of Image Pages:
2 (98,140 Bytes)
Date:
1990-02-09 (February 9, 1990)
Creator:
Johnson, Edward M.
Recipient:
Lederberg, Joshua
Rights:
Reproduced with permission of Edward M. Johnson.
Relation:
Lederberg Grouping: Correspondence F
Box Number: 44
Folder Number: 60
Unique Identifier:
BBBCLK
Accession Number:
104
Document Type:
Letters (correspondence)
Language:
English
Format:
application/pdf
image/tif
Physical Condition:
Good
Series: Correspondence, 1935-2002
SubSeries: 1985-1999
Folder: Johnson, Edward M.
Transcript:
Ed Johnson
[stamped, THE ROCKEFELLER UNIVERSITY OFFICE OF THE PRESIDENT FEB 15 1990]
2-9-90
Dear Dr. Lederberg,
Thank you for the Bardwell review and Craighead reference. I am enclosing a reprint of our paper on asbestos transfection. Did you see the "editorial" by Brooke Mossman et al. in the Science of Jan 19? (Science 247, 294-301). It has some seriously misleading statements and implicit assumptions about chrysotile, and I am drafting a response letter now.
We are currently involved in experiments to directly demonstrate insertional mutagenesis mediated by asbestos in rat mesothelium in vivo. We use a PCR method to amplify up potential insertion sites. The experiments are long ones, and results encouraging
OVER
[written in left margin, PNAS 85: 7670 1988]
[END PAGE ONE]
[BEGIN PAGE TWO]
but not finished yet. We are also looking at the possibility that the p53 tumor suppressor gene is altered (insertional mutagenesis?) in the induction of mesothelioma. We shall keep you apprised.
Sincerely,
ED
[written in different handwriting, (Johnson)]
Metadata Last Modified Date:
2007-01-11
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