We have still not found and justified a credible game for our robot to play. Yet as I tried to tell Klaus the brain needs
a hand as well as an eye to promote its own growth in a reality-oriented context. I should articulate more clearly to the
study section (1) this orientation of our effort and (2) that there are still also prospects of early biomedical utility.
Perceptions (e.g. speech recognition may be a better model of successive, reciprocal refinements of hypothesis and data acquired.
There is certainly much more simulation that could be set up within DENDRAL to justify this approach -- e.g. "intelligent"
search of the dictionaries of solved subproblems which is tantamount to a dynamic manipulation of GOODLIST oriented by data
So whatever the outcome of SUMEX, there is still a lot of introspective research that can be done, the "real time"
instrument being a tape drive.
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But I would like to see us put more imagination into building "hands." I think NSF would be receptive to proposals
for new kinds of instruments; and if we have a lull now we should be thinking of more definitive pre-designs for digitally
controllable mass spectrometers. These will certainly entail new approaches to internal calibration. I wonder about trying
to take something like PFK, seek PFK plus plus, and filter out the near-integral masses (or the PFK plus one that would interfere
with a given sample prob [?]) with a low resolution m.s. that gates the reference ions into the beam
For metastable work we need to learn how to improve m plus yields at low ionization voltages; or alternatively to de-excite
the excited states (collisions with ?)
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Tom -- let's have a session soon say Monday 2 30 to extract lessions [sic] and positive directions from the SUMEX S.V.
(1) What is most chemistry we can do with minimum new hardware e.g. in re Genetics Res. Ctr.
(2) (Simulation mode of real time Dendral) [note to the right, i.e. external memory simulations instrument]
(3) (Better part A Effects) [note to the right, plans for]
[line to, Financial problem?]
(4) hooking onto other PDPIOS on net.
(5) new instrument ideas on ms
continuous internal calibration for HRMS
may need "intelligent control" for gating reference gas
2-D metastable scans
controlling energy of excitation laser inputs in flight? consult Gilda
(6) OTHER Parameters; OTHER AREAS of analysis that might better exercise our ideas of Real Time AI. (What is a more exciting
instrument than GC/ms?)
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whoever can come of the server level
ECL EAF TR
Carl Dj. (opt. for him but urge [?] him if he has some definite ideas
also we must schedule a SIGBIG soonest for general briefing. Friday 23d. at noon [mark to note, ask Ruth to verify whether
my AR date is 3/23 or 3/27] or at 4? or 3/27 or 3/28.
Can Dennis arrange a demo of DENDRAL (any part) for lecture 3/29 8 05 pm at or near Rm 20 University? (Lois Durham ext 4480